Controlling cell migration

Latest research

1. 1. Cell Biology
   2. Neuroscience

   KIS counteracts PTBP2 and regulates alternative exon usage in neurons

   Marcos Moreno-Aguilera, Alba M Neher ... Carme Gallego

   KIS, a kinase upregulated in the developmental brain, phosphorylates the PTBP2 splicing complex and modulates alternative exon usage for proper synaptic spine emergence and maturation.
2. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
3. 1. Neuroscience

   Emergence of brain-like mirror-symmetric viewpoint tuning in convolutional neural networks

   Amirhossein Farzmahdi, Wilbert Zarco ... Tal Golan
4. 1. Cell Biology

   Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

   Simona Bolamperti, Hiroaki Saito ... Hanna Taipaleenmäki

   A novel mechanism underlying the regulation of osteoblast morphology, adherence, and migration that has implications in bone remodeling, regeneration, and response to the pharmacological effects of PTH treatment.
5. 1. Medicine

   Deletion of FNDC5/irisin modifies murine osteocyte function in a sex-specific manner

   Anika Shimonty, Fabrizio Pin ... Lynda F Bonewald

   Analysis of mice lacking the precursor for irisin, FNDC5, provides evidence for a sex-specific role of irisin in calcium release from bone due to osteocytic osteolysis.
6. 1. Structural Biology and Molecular Biophysics

   Dependence of nucleosome mechanical stability on DNA mismatches

   Thuy TM Ngo, Bailey Liu ... Taekjip Ha

   The mechanical stability of a nucleosome is enhanced upon the introduction of a single base pair mismatch that makes DNA more bendable, with implications on mismatch repair in vivo.
7. 1. Medicine
   2. Microbiology and Infectious Disease

   Altered transcriptomic immune responses of maintenance hemodialysis patients to the COVID-19 mRNA vaccine

   Yi-Shin Chang, Kai Huang ... David L Perkins

   Differing time courses of immune responses to the BTN162b2 mRNA COVID-19 vaccination in maintenance hemodialysis subjects are comparable to healthy controls and identify transcriptomic and clinical predictors of anti-spike IgG titers in hemodialysis subjects.
8. 1. Medicine

   Relationship between circulating FSH levels and body composition and bone health in patients with prostate cancer who undergo androgen deprivation therapy: The BLADE study

   Marco Bergamini, Alberto Dalla Volta ... Alfredo Berruti

   Follicle-stimulating hormone in the reference range influences body composition in men exposed to hormone-deprivation therapy for prostate cancer.
9. 1. Neuroscience

   Chronic intermittent hypoxia reveals role of the Postinspiratory Complex in the mediation of normal swallow production

   Alyssa D Huff, Marlusa Karlen-Amarante ... Jan-Marino Ramirez

   Glutamatergic–cholinergic neurons in the postinspiratory complex are critical for swallow motor patterning and the coordination of swallow and breathing, which is disrupted by chronic intermittent hypoxia, a condition seen in many disorders associated with dysphagia and aspiration pneumonia.
10. 1. Neuroscience

    Unifying network model links recency and central tendency biases in working memory

    Vezha Boboeva, Alberto Pezzotta ... Athena Akrami

    Seemingly disparate working memory biases, including short-term serial and contraction biases, may arise from a common mechanism via the interaction of multiple networks, each operating over a distinct timescale.