mTOR signaling and autism

Latest research

1. 1. Developmental Biology
   2. Evolutionary Biology

   The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition

   Zhuqing Wang, Yue Wang ... Wei Yan

   The rapidly evolving X-linked MIR-506 family miRNAs function to enhance sperm competitiveness and male reproductive fitness in mice.
2. 1. Computational and Systems Biology
   2. Genetics and Genomics

   Haplotype function score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits

   Weichen Song, Yongyong Shi, Guan ning Lin

   Using sequence-determined functional genomic features instead of original genotypes can partially overcome challenges in genetic association studies, such as rare variant exclusion and population structure.
3. 1. Neuroscience

   Reactivation strength during cued recall is modulated by graph distance within cognitive maps

   Simon Kern, Juliane Nagel ... Gordon B. Feld
4. 1. Neuroscience

   A dynamic generative model can extract interpretable oscillatory components from multichannel neurophysiological recordings

   Proloy Das, Mingjian He, Patrick L. Purdon
5. 1. Neuroscience

   Adult neurogenesis through glial transdifferentiation in a CNS injury paradigm

   Sergio Casas-Tintó, Nuria García-Guillen, Maria Losada-Pérez
6. 1. Neuroscience

   Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila

   Katharina Eichler, Stefanie Hampel ... Andrew M Seeds

   A synaptic resolution somatotopic map of nearly all mechanosensory neurons on the Drosophila head that individually elicit aimed grooming of specific head locations and collectively elicit a head grooming sequence.
7. 1. Genetics and Genomics
   2. Immunology and Inflammation

   Transposable elements regulate thymus development and function

   Jean-David Larouche, Céline M Laumont ... Claude Perreault

   Multiomic analyses provide new insights into the involvement of transposable elements in T-cell development in the thymus and central tolerance induction.
8. 1. Neuroscience

   Species -shared and -unique gyral peaks on human and macaque brains

   Songyao Zhang, Tuo Zhang ... Tianming Liu

   Having compared cross-species cortical folding patterns between humans and macaques, it is shown that 'Gyral Peaks' can stably exist across different species.
9. 1. Microbiology and Infectious Disease

   Tools and methods for high-throughput single-cell imaging with the mother machine

   Ryan Thiermann, Michael Sandler ... Suckjoon Jun

   A user-friendly pipeline for analysis of time-lapse imaging data from the microfluidic mother machine.
10. 1. Developmental Biology

    Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

    Edgar M Pera, Josefine Nilsson-De Moura ... Ivana Milas

    An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.