Browse the latest research

18,888 results found
    1. Cell Biology

    Zasp52’s differentially expressed intrinsically disordered region confers thin filament stability at the Z-disc

    Nikolai Ho, Frieder Schöck
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Stemness factor Mex3a times translation and protein trafficking to ensure robust differentiation of olfactory sensory neurons

    Martín Escamilla del Arenal, Lauren C Tang ... Rachel Duffié
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Are interphylum spiralian relationships resolvable?

    Ana Serra Silva, Maximilian J Telford
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells

    Noa Nashnaz, Dana Goldberg ... Dan Levy
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    ProteinConformers: large-scale and energetically profiled descriptions of protein conformational landscapes

    Yihang Zhou, Chen Wei ... Yang Zhang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Medicine

    Platelets promote acute liver injury via extracellular vesicles-mediated Aldolase A

    Ruoxue Yang, Jinghua Liu ... Zhao Shan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory

    Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
    Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.
    1. Neuroscience

    Effort produces after-effects costly for others but valued for self

    Ya Zheng, Rumeng Tang
    Neural reward signals following effort are amplified for self-benefiting outcomes but attenuated for other-benefiting outcomes, contingent upon reward magnitude and individual effort sensitivity.
    1. Chromosomes and Gene Expression

    Identification of the regulatory elements and protein substrates of lysine acetoacetylation

    Qianyun Fu, Terry Nguyen ... Y George Zheng
    A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.
    1. Neuroscience

    Subregional activity in the dentate gyrus is amplified during elevated cognitive demands

    Charlotte Castillon, Shintaro Otsuka ... Anis Contractor
    Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.

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