Browse the latest research

18,781 results found
    1. Evolutionary Biology

    Design and experimental characterization of specificity-switching mutational paths of WW domains

    Ahmed Rehan, Eugenio Mauri ... Simona Cocco
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure

    Ian S Prudhomme, Eric R Brooks ... Jennifer A Zallen
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Immunology and Inflammation

    ImPaqT - A Golden Gate-based Toolkit for Zebrafish Transgenesis

    Saskia Hurst, Christiane Dimmler, Mark R Cronan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Evolutionary Biology

    The adaptive landscapes of three global Escherichia coli transcriptional regulators

    Cauã Antunes Westmann, Leander Goldbach, Andreas Wagner
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Challenges in replay detection by TDLM in post-encoding resting state

    Simon Kern, Juliane Nagel ... Gordon B Feld
    Detecting replay during longer time periods (e.g. resting state or sleep) with temporally delayed linear modeling (TDLM) requires biologically implausible event densities, and purely synthetic simulations substantially overestimate the method's sensitivity.
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

    Lori B Koch, Tiasha Ghosh ... Adèle L Marston
    A system to enrich yeast in metaphase of mitosis, meiosis I, or meiosis II reveals reduced spindle assembly checkpoint robustness in meiosis I and distinct kinetochore composition and phosphorylation states.
    1. Neuroscience

    The dominance of large-scale phase dynamics in human cortex, from delta to gamma

    David M Alexander, Laura Dugué
    The phase of cortical activity, measured in the gray matter, is organized at multiple spatial scales, with the largest scales explaining most variance in phase at a given temporal frequency.

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