Browse the latest research

18,412 results found
    1. Cell Biology

    The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism

    Ana Lapão, Lauren Sophie Johnson ... Anne Simonsen
    RAB27A-dependent mitochondrial recruitment of SYTL5 promotes mitophagy and mitochondrial bioenergetics upon hypoxia.
    1. Cell Biology

    Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

    Constanza Salinas-Rebolledo, Javier Blesa ... Alejandro Rojas-Fernandez
    1. Cell Biology

    SMC5/6-mediated plasmid silencing is directed by SIMC1–SLF2 and antagonized by the SV40 large T antigen

    Martina Oravcová, Minghua Nie ... Michael N Boddy
    Distinct SMC5/6 subcomplexes mediate the transcriptional silencing of circular extrachromosomal DNA (SIMC1–SLF2) and repair of chromosomal DNA lesions (SLF1–SLF2), thus enabling exploration of SMC5/6 functions in innate immunity and cancer.
    1. Neuroscience

    Endogenous corazonin signaling modulates the post-mating switch in behavior and physiology in females of the brown planthopper and Drosophila

    Ning Zhang, Shao-Cong Su ... Shun-Fan Wu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Three pathways feed the folate-dependent one carbon pool for growth and virulence of Listeria monocytogenes

    Sandra Freier, Sarah Frentzel ... Sven Halbedel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology

    Nonlinear transcriptional responses to gradual modulation of transcription factor dosage

    Júlia Domingo, Mariia Minaeva ... Tuuli Lappalainen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Ubiquitous predictive processing in the spectral domain of sensory cortex

    Eli Sennesh, Jacob A Westerberg ... Andre Bastos
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution

    Thawann Malfatti, Anna Velica ... Klas Kullander
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    From salience to semantics: multilevel hierarchical contingencies organise parent-infant joint attention

    Pierre Labendzki, Marta Perapoch Amadó ... Sam V Wass
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology

    Learning sequence-function relationships with scalable, interpretable Gaussian processes

    Juannan Zhou, Carlos Martí-Gómez ... David M McCandlish
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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