Browse the latest research

18,656 results found
    1. Immunology and Inflammation
    2. Neuroscience

    Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation

    Collin Laaker, Martin Hsu ... Zsuzsanna Fabry
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions

    Maria Gädeke, Tom Willems ... Johannes Schultz
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Concatenated Modular BK Channel Constructs Reveal Divergent Stoichiometry in Gating Control by LRRC26 (γ1), Pore, and Selectivity Filter

    Guanxing Chen, Qin Li ... Jiusheng Yan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells

    Tanay Ghosh, Roey Baror ... Robin JM Franklin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural basis for the folding of PINK1 by the HSP90–CDC37 chaperone complex

    Kei Okatsu, Hayato Yamamoto ... Shuya Fukai
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Ecology
    2. Evolutionary Biology

    Fitness drivers of division of labor in vertebrates

    Irene García-Ruiz, Dustin Rubenstein
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Solid
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution

    Alastair J Tulloch, Ryan Nicholas Delgado ... Constance L Cepko
    Integrated locus-specific and mutational MPRAs reveal regulatory modules and nucleotide determinants governing cell type-specific gene expression, providing a scalable framework for mapping cis-regulatory architecture.
    1. Cell Biology
    2. Neuroscience

    Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

    Daniel Beaudet, Christopher L Berger, Adam G Hendricks
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics

    Bader Rayan, Eilon Barnea ... Meytal Landau
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

    Jennifer Kosmatka, Cong Liu ... Amy E Keating
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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