Browse the latest research

18,913 results found
    1. Neuroscience

    LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Cell Biology

    Syntaxin11 Deficiency Inhibits CRAC Channel Priming to Suppress Cytotoxicity and Gene Expression in T Lymphocytes

    Sritama Datta, Abhikarsh Gupta ... Monika Vig
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly

    Kai Ding, Beibei Xu ... Yulong He
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Physics of Living Systems

    An engineered multi-step differentiation program in Escherichia coli for self-organized spatial patterning

    Emanuele Boni, Hélène Siboulet ... Yolanda Schaerli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Developmental Biology

    Tatton-Brown-Rahman Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

    Gareth Chapman, Julianna J Determan ... Kristen L Kroll
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Isolation of small extracellular vesicles from small volumes of blood plasma using size exclusion chromatography and density gradient ultracentrifugation

    Fang Kong, Megha Upadya ... Ming Dao
    The optimized protocol for isolating small extracellular vesicles from small blood volumes, confirmed by independent methods including cryo-electron microscopy, ensures superior purity and high yield for reliable biomarker detection.
    1. Neuroscience

    Sexual dimorphism in sensorimotor transformation of optic flow

    Sarah Nicholas, Katja Sporar Klinge ... Karin Nordström
    Descending neurons that encode widefield motion vision in the fly have sexually dimorphic velocity tuning, while the wing beat amplitude, which these neurons presumably control, is monomorphic.
    1. Neuroscience

    Involuntary feedback responses reflect a representation of partner actions

    Seth R Sullivan, John H Buggeln ... Joshua GA Cashaback
    High-level partner representations tune low-level visuomotor reflexes.
    1. Structural Biology and Molecular Biophysics

    Conformational Variability of HIV-1 Env Trimer and Viral Vulnerability

    Yiwei Cao, Wonpil Im
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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