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19,324 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A Sterol-Binding Cavity Underlies Sterol Recognition and Differential Activation of the ABCG5/G8

    Fatemeh Rezaei, Isra F Omar ... Jyh-Yeuan Lee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cross-Kingdom Control: Yeast Prion Protein [MRPL10+] Modulates Host Physiology in Drosophila

    Chih-Chun Janet Lin, Jessica Y Jiang ... Andrew G Clark
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Evolutionary Biology

    Fitness flux in SARS-CoV-2 and influenza H3N2

    Trevor Bedford
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Glia regulate local retinoic acid levels to specify neuronal specialisation for high-acuity vision

    Manuela Lahne, Roxana Lungu ... Ryan B MacDonald
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Identifying Novel Estrogenic Mitochondrial Targets in Hypothalamic Proopiomelanocortin Neurons by Chemoproteomics

    Jian Qiu, Martha A Bosch ... Martin J Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Real-Time Embodied Experience Shapes High-Level Reasoning Under Altered Gravity

    Hélène Grandchamp des Raux, Tommaso Ghilardi ... Ori Ossmy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology

    A stress-responsive morphogenetic program of the uterine epithelium safeguards the establishment of early pregnancy

    Chihiro Ishizawa, Shizu Aikawa ... Yasushi Hirota
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Single neurons detect spatiotemporal activity transitions through STP and EI imbalance

    Aditya Asopa, Upinder Singh Bhalla
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    In vivo virus-free lineage tracing and live imaging reveal that NeuroD1 does not reprogram microglia into neurons

    Xiaoyu Li, Yuxin Li ... Yanxia Rao
    Genetic lineage tracing and live-cell imaging demonstrate that NeuroD1 does not convert microglia into neurons but instead promotes microglial apoptosis, challenging claims of in situ glia-to-neuron conversion.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Meiotic axis protein deposition and double-strand break formation near yeast chromosome ends are regulated by multiple distinct layers of regulation, including the chromatin modifiers Sir2/3 and Dot1.
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