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19,312 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation

    Chloé I Charendoff, Félix V Louchez ... Agathe Subtil
    The metabolic pressure exerted by a pathogen with an intracellular lifestyle drives epigenetic modifications, which modulate the transcriptional response of the host to infection.
    1. Biochemistry and Chemical Biology

    NUDT2 loss defines quantitative limits for dinucleoside polyphosphate action on the cGAS–STING–TBK1 axis

    Paul Weiland, Renuka Dharani Shivakumar ... Gert Bange
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Glycolipid MPIase is essential for the TAT (Twin-Arginine Translocation) pathway

    Hanako Nishikawa, Nachi Yamamoto ... Ken-ichi Nishiyama
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Solid
    1. Physics of Living Systems

    Mechanics and fate stochasticity shape stem cell distribution in tissues

    Johannes C Krämer, Edouard Hannezo, Jens Elgeti
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Immunology and Inflammation

    Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation

    Robin Bartolini, Deepika Sharma ... Gerard J Graham
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

    Jennifer Kosmatka, Cong Liu ... Amy E Keating
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience
    2. Physiology

    Fitness Level, but not Sex, affects Exercise-Induced Pain Modulation

    Janne I Nold, Tahmine Fadai ... Christian Büchel
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Striatal dopamine and serotonin release operate largely in parallel with limited, asymmetric crosstalk

    Fabrice Chaudun, Yu Liu ... Christian Lüscher
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Convincing
    1. Neuroscience

    Reduced dorsal CA1 activity limits retention of the temporal component of declarative memory in the Cntnap2 knockout mouse model of autism

    Elise Caitlin Rawlinson, Michael Hugh McCullough ... Nathalie Dehorter
    Restoring hippocampal CA1 activation during temporal gaps is sufficient to rescue long-term memory in a mouse model of autism.
    1. Biochemistry and Chemical Biology

    Gluconeogenic compensation renders glycogen phosphorylase non-essential as an insecticidal target in Plutella xylostella

    Yifei Zhou, Yanqi Kang ... Jiyuan Liu
    Gluconeogenesis rescues insects from glycogen phosphorylase suppression, establishing metabolic redundancy as a key consideration for insecticide target selection.
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