Browse the latest research

19,269 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control

    Pankaj Kumar Gupta, Timothy H Murphy
    The open-source closed-loop system enables mice to learn modulation of cortical activity or movement by providing a platform for testing brain-behavior relationships in motor learning and neurorehabilitation research.
    1. Neuroscience

    Developmental synchrony of retinal waves, apoptosis, and angiogenesis in postnatal retina

    Michael A Savage, Cori Bertram ... Evelyne Sernagor
    An interdisciplinary approach uncovers a never-before-seen multifaceted synchrony of developmental processes in the rodent retina which are driven by purinergic signalling from apoptotic retinal ganglion cells.
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Tooth plucking triggers a rapid, coordinated regeneration program in cichlids, accelerating replacement more than threefold through temporally organized epithelial, mesenchymal, immune, vascular, and neural signaling.
    1. Biochemistry and Chemical Biology

    Integrated respirometry and metabolomics unveil circadian metabolic dynamics in Drosophila

    Farheen Akhtar, Dania M Malik ... Aalim Weljie
    Wild-type flies anticipate daily respiratory demands by coordinating substrate use, whereas short-sleep and clock-deficient mutants shift toward reactive fuel use and altered redox metabolism.
    1. Developmental Biology
    2. Evolutionary Biology

    The tuxedo sea urchin Mespilia globulus: A fast-developing and tractable model for genomic and developmental biology

    Omar Matar, Marie Emilie Maeland ... Ferdinand Marlétaz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Parallel connectivity and genomic divergence but heterogeneous demographic history in sympatric Mediterranean clingfishes

    Maximilian Wagner, Stephan Koblmüller ... Hannes Svardal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology

    Lateral opening site of human oligopeptide transporter 2 plays a key role in the interaction with polymyxins

    Xukai Jiang, Yining Luo ... Jian Li
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    Spectraplakin is required for dendritic microtubule organization via a tip-based mechanism

    Matthew Davies, Neeraja Sanal ... Sebastian Rumpf
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Ecology
    2. Neuroscience

    Machine learning of honey bee olfactory behavior identifies repellent odorants in free-flying bees in the field

    Joel Kowalewski, Barbara F Baer-Imhoof ... Anandasankar Ray
    Honey bee olfactory aversion can be modeled using machine learning to iteratively discover bee-selective repellents, validated in free-flying assays, that can potentially reduce contact with pesticides.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Neuroscience

    Region-specific mechanosensation modulates Drosophila postural control behaviour

    William Roseby, Jonathan AC Menzies ... Claudio R Alonso
    Behavioural, optogenetic, and gene expression analyses demonstrate that regional mechanosensory processes instructed by Hox gene inputs are essential for postural control in Drosophila larvae linking local body features to behaviour.

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