Browse the latest research

19,293 results found
    1. Immunology and Inflammation

    Heterogeneity and ontogeny of mouse thymic macrophages reveal a requirement for Csf1r-expressing myeloid cells during early T cell development

    Helen Wang, Vinothkumar Rajan ... Juan Carlos Zúñiga-Pflücker
    Two thymic macrophage subsets differ in developmental origin and specialize in apoptotic-cell clearance or immune signaling, linking the thymic myeloid niche to progression through the early β-selection-associated checkpoint.
    1. Evolutionary Biology

    Large scale loss-of-function mutations during chicken evolution and domestication

    Siwen Wu, Kun Wang ... Zhengchang Su
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Golgi CATCHR complexes function as organizing hubs for vesicle tethering and fusion

    Walter S Aragon-Ramirez, Amrita Khakurel ... Vladimir V Lupashin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    On the Polymorph-Selection Determinants of α-Synuclein Amyloid Fibrils Studied at Atomic Resolution

    Lukas Frey, David Rhyner ... Jason Greenwald
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    GDNF regenerates the missing enteric nervous system of Hirschsprung mice via non-canonical signaling in diverse subtypes of tissue-resident progenitors

    Alassane Gary, Rodolphe Soret ... Nicolas Pilon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cis-regulation and natural selection in the evolution of human DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
    1. Neuroscience

    Improved inference of latent neural states from calcium imaging data

    Stephen Keeley, David Zoltowski ... Jonathan Pillow
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

    Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Fitting bifurcation structure, not voltage traces: Reduced neuron models that preserve physiological parameter dependence

    Louisiane Lemaire, Mahraz Behbood ... Susanne Schreiber
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
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