Browse the latest research

19,270 results found
    1. Biochemistry and Chemical Biology

    Glycolipid MPIase is essential for the TAT (Twin-Arginine Translocation) pathway

    Hanako Nishikawa, Nachi Yamamoto ... Ken-ichi Nishiyama
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Large scale prospective evaluation of co-folding across hundreds of Mac1-ligand complexes and three virtual screens

    Jongbin Kim, Galen J Correy ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

    Vincent Hisler, Lana Rees ... Anna Jaźwińska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Neuroscience

    Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex

    Ryan W Kirk, Liwei Sun ... Sacha Nelson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via the CCR5/ERK/CREB Pathway

    Jingxiu Li, Keyuan Gao ... Chenxi Sun
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control

    Pankaj Kumar Gupta, Timothy H Murphy
    The open-source closed-loop system enables mice to learn modulation of cortical activity or movement by providing a platform for testing brain-behavior relationships in motor learning and neurorehabilitation research.
    1. Neuroscience

    Developmental synchrony of retinal waves, apoptosis, and angiogenesis in postnatal retina

    Michael A Savage, Cori Bertram ... Evelyne Sernagor
    An interdisciplinary approach uncovers a never-before-seen multifaceted synchrony of developmental processes in the rodent retina which are driven by purinergic signalling from apoptotic retinal ganglion cells.
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Tooth plucking triggers a rapid, coordinated regeneration program in cichlids, accelerating replacement more than threefold through temporally organized epithelial, mesenchymal, immune, vascular, and neural signaling.

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