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19,337 results found
    1. Developmental Biology

    Gcn5 and mTORC1 mediated regulation of autophagy controls Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A Spatiotemporal Hierarchy for Social Interaction Perception in the Lateral Visual Stream

    Emalie McMahon, Elizabeth Jiwon Im ... Leyla Isik
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    ITK deficiency protects against autoimmune pulmonary hemorrhage by promoting Amphiregulin-producing regulatory T cells

    Mohammad Saddam Hossain, Ali Mobeen ... Mobin Karimi
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Neuroscience

    Hierarchical Neural Circuit Theory of Normalization and Inter-areal Communication

    Asit Pal, Shivang Rawat ... Stefano Martiniani
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Open source laser-scanning photostimulation for neuroscience with Zapit

    Michael Lohse, Oliver M Gauld ... Robert AA Campbell
    A validated, open design brings programmable non-invasive photostimulation of multiple cortical areas in behaving mice to labs without expertise in optics or software design.
    1. Ecology
    2. Plant Biology

    Genetic canalization of nutrient resorption in the widespread grass Phragmites australis under salt stress

    Lele Liu, Wenyi Sheng ... Weihua Guo
    Salinity does not alter nutrient resorption efficiency, which is instead shaped by phylogeographic history and latitude.
    1. Cell Biology

    Small brown planthopper infestation enhances it reproduction and insecticide tolerance by manipulating glucose distribution and levels in rice

    Hainan Zhang, Qi Zhang ... Jianjun Wang
    Small brown planthopper infestation drives rice glucose redistribution to boost its own reproduction and insecticide tolerance.
    1. Neuroscience

    The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells

    Tanay Ghosh, Roey Baror ... Robin JM Franklin
    gSWITCH identifies dynamic lineage switch genes and reveals BCL11A as an evolutionarily conserved regulator whose restoration rescues age-impaired oligodendrocyte progenitor cell differentiation.
    1. Biochemistry and Chemical Biology

    SARS-CoV-2 main protease inhibition through dimerization promotion by peptidomimetic inhibitors and disruption by ebselen

    Chengxi Liu, Qinyu Jia ... Zhong-Ping Yao
    Distinct effects of peptidomimetic inhibitors and ebselen on SARS-CoV-2 main protease dimerization reveal new strategies for antiviral drug design.
    1. Structural Biology and Molecular Biophysics

    Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching

    Kexin Zhang, Timothy Grant, Nikolaus Grigorieff
    High-resolution structural information can be recovered from proteins well below the conventional cryo-electron microscopy size range, substantially extending the range of complexes accessible to structural analysis.
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