Morgane Vandendoren, Jason G Landen ... Adam Nelson
Oxytocin neurons couple physiological warming to behavioral arousal, revealing a homeostatic mechanism that coordinates transitions between low- and high-energy states.
Simulation-based inference predicts putative circuit mechanisms of hyperexcitability in a phenomenological microcircuit simulator with more than 30 free intrinsic and synaptic parameters.
The interaction of important signaling pathway members identified through in silico and in vitro approaches provides a model that suggests local receptor multimerization through bridging functions of various ligands.
A large-scale convergence gradient and a fine-scale divergence gradient in cortical architecture capture visual hierarchy, areal boundaries, and behavior, uncovering an undescribed retinotopic representation in anterior temporal cortex.
The supraspinal system of larval zebrafish has been described, uncovering spinal projections from the telencephalon, mesencephalon, and rhombencephalon, as well as numerous motor and neuromodulatory nuclei conserved with mammals.
Mapping the molecular interactions between polymyxins and hPepT2 enables rational design of safer lipopeptide antibiotics with reduced renal toxicity while retaining antibacterial activity.
In the presence of emulated cone loss, eye movements are used to gather and integrate information, leading to improved letter acuity compared to a non-moving condition.