Browse the latest research

19,267 results found
    1. Microbiology and Infectious Disease

    Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach

    Nisheeth Agarwal, Himanshu Gogoi ... Bappaditya Dey
    A well-orchestrated machinery for L-leucine uptake is functional in Mycobacterium tuberculosis, which is important for the intracellular survival of the tuberculosis (TB) pathogen.
    1. Microbiology and Infectious Disease

    A novel rapid host cell entry pathway determines the intracellular fate of Staphylococcus aureus

    Marcel Rühling, Fabio Schmelz ... Martin J Fraunholz
    An acid sphingomyelinase-dependent rapid uptake pathway for the pathogen Staphylococcus aureus is linked to altered intracellular infection dynamics.
    1. Cancer Biology

    Microbial Metabolites Potentiate MAIT Cell Anti-Tumor Immunity Against Solid Tumors

    Yichen Zhu, Xinyuan Shen ... Lili Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    A Quartet of Native Orai Channel Isoforms Orchestrates Graded NFAT Activation and Transcription

    Ahmed Emam Abdelnaby, Yin-Hu Wang ... Mohamed Trebak
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Covert attention dynamically shapes decision making

    Amy X Li, Benjamin Chan ... Laurence T Hunt
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Focused ultrasound alters neural time irreversibility independently of response amplitude

    Jacek P Dmochowski, David H Wolpert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Physics of Living Systems

    Anatomy and mechanics of tsetse fly blood feeding

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    Molecular and Functional Analysis of Calcium Binding by a Cancer-linked Calreticulin Mutant

    Ishmael Nii Ayibontey Tagoe, Amanpreet Kaur ... Malini Raghavan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    A unifying model of T-cell signaling protein condensates in reconstitution experiments

    Yannick Azhri Din Omar, Simou Sun ... Arup K Chakraborty
    The formation of biomolecular condensates by multivalent membrane proteins is delayed by slow crosslinking dynamics, with a variety of condensate morphologies emerging under different experimental conditions.
    1. Cell Biology

    Wound-induced syncytia outpace mononucleate neighbors during Drosophila wound repair

    James S White, Junmin Hua ... Andrea Page-McCaw
    In vivo live imaging, quantitative analysis, and computational modeling reveal that wound-induced epithelial cell fusion accelerates epithelial repair through several likely mechanisms.

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