Browse the latest research

19,338 results found
    1. Neuroscience

    Oxytocin neurons signal state-dependent transitions from rest to thermogenesis and behavioral arousal

    Morgane Vandendoren, Jason G Landen ... Adam Nelson
    Oxytocin neurons couple physiological warming to behavioral arousal, revealing a homeostatic mechanism that coordinates transitions between low- and high-energy states.
    1. Neuroscience

    Compensation of hyperexcitability with simulation-based inference

    Daniel Müller-Komorowska, Tomoki Fukai
    Simulation-based inference predicts putative circuit mechanisms of hyperexcitability in a phenomenological microcircuit simulator with more than 30 free intrinsic and synaptic parameters.
    1. Cell Biology

    SVEP1 enables efficient binding of angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

    Katharina Uphoff, Melina Hußmann ... Dörte Schulte-Ostermann
    The interaction of important signaling pathway members identified through in silico and in vitro approaches provides a model that suggests local receptor multimerization through bridging functions of various ligands.
    1. Neuroscience

    Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

    Xiayu Chen, Xingyu Liu ... Jesse Gomez
    A large-scale convergence gradient and a fine-scale divergence gradient in cortical architecture capture visual hierarchy, areal boundaries, and behavior, uncovering an undescribed retinotopic representation in anterior temporal cortex.
    1. Neuroscience

    Applying functional MRI analysis techniques to whole-brain calcium-imaging data to investigate structural and functional relationships in Drosophila melanogaster

    Takuto Okuno, Alexander Woodward ... Junichi Hata
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Unique longitudinal contributions of sulcal interruptions to reading acquisition in children

    Florence Bouhali, Jessica Dubois ... Kevin S Weiner
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Whole-brain mapping of spinal-projecting neurons in larval zebrafish

    Martin Carbo-Tano, Kevin Fidelin ... Claire Wyart
    The supraspinal system of larval zebrafish has been described, uncovering spinal projections from the telencephalon, mesencephalon, and rhombencephalon, as well as numerous motor and neuromodulatory nuclei conserved with mammals.
    1. Biochemistry and Chemical Biology

    Lateral opening site of human oligopeptide transporter 2 plays a key role in the interaction with polymyxins

    Xukai Jiang, Yining Luo ... Jian Li
    Mapping the molecular interactions between polymyxins and hPepT2 enables rational design of safer lipopeptide antibiotics with reduced renal toxicity while retaining antibacterial activity.
    1. Neuroscience

    Revealing the benefit of eye motion for acuity under emulated cone loss

    Hannah K Doyle, James Fong ... Austin Roorda
    In the presence of emulated cone loss, eye movements are used to gather and integrate information, leading to improved letter acuity compared to a non-moving condition.

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