Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Chromosomes and Gene Expression

    Epigenetics: Linking environmental factors and gene regulation

    Signe Penner-Goeke, Elisabeth B Binder
    A technique called mSTARR-seq sheds light on how DNA methylation may shape responses to external stimuli by altering the activity of sequences that control gene expression.
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    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Chromatin Remodeling: The voyage is as important as the harbor

    Anton Sabantsev, Sebastian Deindl
    To find nucleosomes, chromatin remodelers slide and hop along DNA, and their direction of approach affects the direction that nucleosomes slide in.
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    1. Neuroscience

    Proteostress: Mechanosensory neurons under pressure

    Erin Cram
    A build-up of eggs in the uterus of the nematode C. elegans triggers the release of large extracellular vesicles, called exophers, from neurons that are sensitive to mechanical forces.
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    1. Neuroscience

    Perception: How larvae feel the world around them

    Jimena Berni
    A complete map of the external sense organs shows how fruit fly larvae detect different aspects of their environment.
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    1. Neuroscience

    Visual System: Wiring up for controlled flight

    Albert Cardona
    A map showing how neurons that process motion are wired together in the visual system of fruit flies provides new insights into how animals navigate and remain stable when flying.
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    1. Evolutionary Biology

    Computational Biology: Capturing the unpredictability of stem cells

    Arda Durmaz, Valeria Visconte
    A new mathematical model that can be applied to both single-cell and bulk DNA sequencing data sheds light on the processes governing population dynamics in stem cells.
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    1. Structural Biology and Molecular Biophysics

    Archaea: Exploring surface structures

    Bernhard Schuster
    The surface layer of Sulfolobus acidocaldarius consists of a flexible but stable outer protein layer that interacts with an inner, membrane-bound protein.
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    1. Neuroscience

    Computational Neuroscience: Building a mathematical model of the brain

    Frances Skinner
    Automatic leveraging of information in a hippocampal neuron database to generate mathematical models should help foster interactions between experimental and computational neuroscientists.
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    1. Microbiology and Infectious Disease

    Stress Adaptation: Adapting to ever-changing conditions

    Serge Pelet
    Experiments involving periodic stimuli shed light on the interplay between hyper-osmotic stress and glucose starvation in yeast cells.
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    1. Chromosomes and Gene Expression

    Translation: It’s a competitive business

    Masaaki Sokabe, Christopher S Fraser
    A new in vitro system called Rec-Seq sheds light on how mRNA molecules compete for the machinery that translates their genetic sequence into proteins.
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