Figure 1.

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Recognition of familiar food activates feeding via an endocrine serotonin signal in Caenorhabditis elegans

Figure 1.

Figure 1.
Download figureOpen in new tabDownload powerpointFigure 1. Recognition of familiar food increases feeding response in C. elegans. The memory of familiar food lasts for at least 7 hr.

(A) Experimental design for the feeding assay. The periods during which animals were exposed to HB101, DA1878, and starvation are shown in blue, red, and white, respectively. Each condition is coded by two letters representing the training and test food in order. H and D represent HB101 and DA1878, respectively. (B)–(C) Feeding rates of wild-type worms on HB101 (B) and DA1878 (C) just after training the animals on one or the other bacterium. (D)–(E) Feeding rates of wild-type worms on HB101 (D) and DA1878 (E) after a 7- to 8-hr interval from training the animals on one or the other bacterium. Data shown as mean ± SEM, ***p<0.001, unpaired t-test and Mann–Whitney U test (two-tailed). The number of animals tested (n ≥ 3 independent assays for each group) is shown in parenthesis.

DOI: http://dx.doi.org/10.7554/eLife.00329.003