Figure 2. | Recognition of familiar food activates feeding via an endocrine serotonin signal in Caenorhabditis elegans

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Recognition of familiar food activates feeding via an endocrine serotonin signal in Caenorhabditis elegans

Figure 2.

Figure 2.
Download figureOpen in new tabDownload powerpointFigure 2. Recognition of familiar food increases feeding response in C. elegans. The memory of familiar food lasts for at least 7 hr.

(A) Experimental design for the feeding assay. The periods during which animals were exposed to HB101, JU54 or PA14 pstP, and starvation are denoted blue, red, and white, respectively. Each condition is coded by two letters representing the training and test foods in order. H, J and P represent HB101, JU54 and PA14 pstP, respectively. (B)–(C) Feeding rates of wild-type worms on HB101 (B) and JU54 (C) after a 7- to 8-hr interval from training the animals on one or the other bacterium. (D)–(E) Feeding rates of wild-type worms on HB101 (D) and PA14 pstP (E) after a 7- to 8-hr interval from training the animals on one or the other bacterium. Data shown as mean ± SEM, ***p<0.001, unpaired t-test and Mann–Whitney U test (two-tailed). The number of animals tested (n ≥ 3 independent assays per each group) is shown in parentheses.

DOI: http://dx.doi.org/10.7554/eLife.00329.004