Figure 6.

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Recognition of familiar food activates feeding via an endocrine serotonin signal in Caenorhabditis elegans

Figure 6.

Figure 6.
Download figureOpen in new tabDownload powerpointFigure 6. Feeding rates of wild type and five serotonin receptor null mutants in presence of serotonin.

Among five serotonin receptor null mutants, only ser-7(tm1325) failed to activate feeding in response to serotonin. A null mutation in ser-4 also decreased the feeding rate in presence of serotonin but the effect was relatively small. These assays were conducted on 3- to 5-hr-old L1 larvae, which pumped much more slowly than the adults used in other measurements. The average values of the feeding rates presented in this figure are 73.6 ± 3.3, 63.5 ± 6.2, 52.1 ± 5.4, 82.3 ± 10.5, 12.2 ± 1.8 and 90.9 ± 11.6 in order. *p<0.05, ***p<0.001; one-way ANOVA, post hoc Tukey test. The number of animals tested (n ≥ 2 independent assays per each group) is shown at the bottom of the bar.

DOI: http://dx.doi.org/10.7554/eLife.00329.008