13,043 results found
    1. Computational and Systems Biology
    2. Developmental Biology

    Large-scale analysis and computer modeling reveal hidden regularities behind variability of cell division patterns in Arabidopsis thaliana embryogenesis

    Elise Laruelle, Katia Belcram ... Philippe Andrey
    Self-organization based on a feedback loop between cell geometry and division plane positioning plays a central role in the building of tissue architectures in Arabidopsis thaliana embryo through both stereotyped and variable division patterns.
    1. Microbiology and Infectious Disease

    A conserved cell division protein directly regulates FtsZ dynamics in filamentous and unicellular actinobacteria

    Félix Ramos-León, Matthew J Bush ... Susan Schlimpert
    Identification of a novel regulator that directly influences the assembly and function of the cell division machinery in industrially and medically important bacteria.
    1. Cell Biology
    2. Developmental Biology

    Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division

    Felipe Mora-Bermúdez, Fumio Matsuzaki, Wieland B Huttner
    Mammalian neural stem cells specifically regulate a subset of astral microtubules to govern the subtle changes in spindle orientation that underlie symmetric vs asymmetric cell division during embryonic cortical neurogenesis.
    1. Cell Biology
    2. Computational and Systems Biology

    CDK control pathways integrate cell size and ploidy information to control cell division

    James Oliver Patterson, Souradeep Basu ... Paul Nurse
    DNA concentration, cyclin levels, phosphatase activity, and CDK phosphorylation combine to directly link cell size to cell division.
    1. Developmental Biology
    2. Neuroscience

    Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

    Tamsin J Samuels, Aino I Järvelin ... Ilan Davis
    Single molecule mRNA imaging uncovers post-transcriptional regulation of myc mRNA, via a cell-intrinsic mechanism allowing individualised control of neural stem cell proliferation during Drosophila brain development.
    1. Cell Biology
    2. Computational and Systems Biology

    Bistability of a coupled Aurora B kinase-phosphatase system in cell division

    Anatoly V Zaytsev, Dario Segura-Peña ... Ekaterina L Grishchuk
    Self-activating Aurora B kinase, opposed by an inhibitory phosphatase, forms spatial phosphorylation patterns during cell division.
    1. Plant Biology

    Tuning self-renewal in the Arabidopsis stomatal lineage by hormone and nutrient regulation of asymmetric cell division

    Yan Gong, Julien Alassimone ... Dominique C Bergmann
    Quantitative live-cell time-lapse imaging reveals that the spatial and temporal degree of cortical polarity domains reflects stem-cell division capacity in cells of the Arabidopsis plant leaf epidermis.
    1. Microbiology and infectious disease

    Asymmetric division triggers cell-specific gene expression through coupled capture and stabilization of a phosphatase

    Niels Bradshaw, Richard Losick
    Asymmetric cell division is linked to cell-specific transcription by handoff of a key developmental regulator from the cytokinetic machinery to the adjacent cell pole where it oligomerizes to become stabilized and activated.
    1. Cell Biology

    A new class of cyclin dependent kinase in Chlamydomonas is required for coupling cell size to cell division

    Yubing Li, Dianyi Liu ... James G Umen
    CDKG1 is a D-cyclin dependent retinoblastoma related protein kinase whose abundance scales with cell size and controls cell division cycle number during multiple fission.
    1. Microbiology and Infectious Disease

    Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

    Andrew N Gray, Alexander JF Egan ... Waldemar Vollmer
    The protein CpoB regulates PBP1B activity in response to the Tol energy state, which facilitates feedback and synchronicity between envelope constriction processes during Gram-negative bacterial cell division.

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