5,838 results found
    1. Neuroscience

    Quantitative properties of a feedback circuit predict frequency-dependent pattern separation

    Oliver Braganza, Daniel Mueller-Komorowska ... Heinz Beck
    The feedback inhibitory microcircuit of the dentate gyrus likely boosts pattern separation during gamma oscillations.
    1. Neuroscience

    Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice

    Wei Deng, Mark Mayford, Fred H Gage
    By using different groups of cells to represent distinct environments and events, the dentate gyrus of the hippocampus helps to keep memories of similar events separate.
    1. Neuroscience

    Extra-hippocampal contributions to pattern separation

    Tarek Amer, Lila Davachi
    The ability to discriminate highly overlapping events in memory is a multistage process supported by a network of brain regions and neocortical–hippocampal interactions.
    1. Neuroscience

    Successful retrieval of competing spatial environments in humans involves hippocampal pattern separation mechanisms

    Colin T Kyle, Jared D Stokes ... Arne D Ekstrom
    Functional magnetic resonance imaging and multivariate pattern analysis reveal remapping-like behavior during successful retrieval of competing environments, while unsuccessful retrieval is accompanied by reinstatement of interfering representations.
    1. Neuroscience

    Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

    Wankun L Li, Monica W Chu ... Takaki Komiyama
    Adult-born neurons in the olfactory bulb allow state-dependent pattern separation of representations of similar odorants.
    1. Neuroscience

    Adult-born granule cells mature through two functionally distinct states

    János Brunner, Máté Neubrandt ... János Szabadics
    3-10 weeks old adult-born granule cells provide two temporally overlapping but functionally distinct neuronal cell populations by being sensitive to distinct aspects of their inputs.
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    1. Neuroscience

    Synchronous activity patterns in the dentate gyrus during immobility

    Martin Pofahl, Negar Nikbakht ... Heinz Beck
    Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.
    1. Neuroscience

    Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks

    Jia-Min Zhuo, Hua-an Tseng ... Xue Han
    Adult neurogenesis, although happening at a slow rate in the adult brain, plays an important role in learning and memory and has the ability to powerfully modulate large scale neural networks.
    1. Neuroscience

    Nonlinear transient amplification in recurrent neural networks with short-term plasticity

    Yue Kris Wu, Friedemann Zenke
    The interplay of recurrent excitation and short-term plasticity enables nonlinear transient amplification, an ideal mechanism for selective amplification, pattern completion, and pattern separation in recurrent neural networks.
    1. Computational and Systems Biology
    2. Neuroscience

    A functional model of adult dentate gyrus neurogenesis

    Olivia Gozel, Wulfram Gerstner
    The GABA input switching from excitatory to inhibitory during maturation of adult-born dentate granule cells is crucial for their integration into the preexisting circuit.

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