390 results found
    1. Neuroscience

    Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse

    Erica Tagliatti, Manuela Fadda ... Anna Fassio
    The small GTPase Arf6 plays a role in setting the size of the readily releasable pool of synaptic vesicles and in the definition of the recycling route for endocytosed vesicles.
    1. Cell Biology
    2. Neuroscience

    A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

    Yumei Wu, Eileen T O'Toole ... Pietro De Camilli
    Analysis of neurons that lack the two neuronal dynamins, dynamin 1 and 3, demonstrates a pathway of synaptic vesicle reformation that does not require these two dynamins or clathrin-dependent budding.
    1. Cell Biology
    2. Neuroscience

    Synaptic activity regulates AMPA receptor trafficking through different recycling pathways

    Ning Zheng, Okunola Jeyifous ... William N Green
    There are at least two separate pathways for AMPA receptor recycling, which are regulated by synaptic activity.
    1. Cell Biology
    2. Plant Biology

    Delivery of endocytosed proteins to the cell–division plane requires change of pathway from recycling to secretion

    Sandra Richter, Marika Kientz ... Gerd Jürgens
    The same membrane trafficking cargo can change pathways mediated by different members of ARF-GEF family of vesicle formation regulators.
    1. Neuroscience

    Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice

    Yuji Okamoto, Noa Lipstein ... Mitsuharu Midorikawa
    Capacitance measurements and pH imaging reveal distinct modes of uptake for endocytotic presynaptic membrane and proteins.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling

    Rajan Thakur, Aniruddha Panda ... Padinjat Raghu
    Phosphatidic acid regulates recycling of endocytosed plasma membrane vesicles in polarized cells through a retromer and Arf1 dependent process.
    1. Cell Biology

    Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5

    Michel Becuwe, Sébastien Léon
    A novel regulatory step in the endocytic pathway, which occurs post-internalization, takes place at the trans-Golgi network and involves the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5.
    1. Cell Biology

    Caveolae couple mechanical stress to integrin recycling and activation

    Fidel-Nicolás Lolo, Dácil María Pavón ... Miguel A del Pozo
    Caveolae regulate integrin mechanosensing by establishing a force threshold for activation and recycling.
    1. Cell Biology

    A novel live-cell imaging assay reveals regulation of endosome maturation

    Maria Podinovskaia, Cristina Prescianotto-Baschong ... Anne Spang
    A novel, inexpensive, easy-to-use method to analyse traffic along the endosomal pathway in mammalian cells shows that there is coordination between Rab conversion and acidification, but almost none between Rab conversion and recycling.
    1. Neuroscience

    Optical detection of three modes of endocytosis at hippocampal synapses

    Natali L Chanaday, Ege T Kavalali
    Single synaptic vesicle imaging shows that kinetically distinct endocytic pathways are differentially regulated by calcium and temperature, and influence the fidelity of synaptic vesicle protein retrieval.

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