Highlights

  • Special Issue: Reproductive Health

    There is a clear need for a better understanding of the fundamental biology of reproduction and for new treatments for a range of reproductive disorders.

    Collection
  • New mechanism for mass escape

    The release of small extracellular vesicles from a larger membrane-enclosed structure can be described by a ‘torn bag’ mechanism.

    Tamás Visnovitz, Dorina Lenzinger ... Edit I Buzas
    Short Report
  • P63+ stem cells go on trial

    The results of a phase 1 clinical trial in which P63+ stem cells were given to patients with idiopathic pulmonary fibrosis are reported.

    Shiyu Zhang, Min Zhou ... Wei Zuo
    Reviewed Preprint Updated

Latest research

    1. Plant Biology

    Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution

    Soham Mukhopadhyay, Muhammad Asim Javed ... Edel Pérez-López
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

    Jacob W Klemm, Chloe Van Hazel, Robin E Harris
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Evolutionary Biology

    Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism

    Adrian Paramo Blazquez, Pedro Mocho ... Francisco Ortega
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Structure and Cl- Conductance Properties of the Open State of Human CFTR

    Zhi-Wei Zeng, Christopher E Ing, Régis Pomès
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology

    ANKRD5: a key component of the axoneme required for sperm motility and male fertility

    Shuntai Yu, Guoliang Yin ... Fengchao Wang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome

    Huei Bin Wang, Natalie E Smale ... Christopher S Colwell
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology

    Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota

    Zhiheng Li, Jinsheng Hu ... Julia A Clarke
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Genetics and Genomics

    UBR-1 deficiency leads to ivermectin resistance in C. elegans

    Yi Li, Long Gong ... Shangbang Gao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Afadin Sorts Different Retinal Neuron Types into Accurate Cellular Layers

    Matthew R Lum, Sachin H Patel ... Xin Duan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

    Joshua G Medina-Feliciano, Griselle Valentín-Tirado ... José E García-Arrarás
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing