Highlights

Latest research

    1. Cell Biology
    2. Neuroscience

    CellSeg3D: self-supervised 3D cell segmentation for light-sheet microscopy

    Cyril Achard, Timokleia Kousi ... Mackenzie Weygandt Mathis
    Revised
    Reviewed Preprint v2
    Updated
    1. Cancer Biology

    Oncogenic and teratogenic effects of p53Y217C, a mouse model of the human hotspot mutant p53Y220C

    Sara Jaber, Eliana Eldawra ... Franck Toledo
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Activity-dependent lateral inhibition enables the synchronization of olfactory bulb projection neurons

    Tal Dalal, Rafi Haddad
    Revised
    Reviewed Preprint v2
    Updated
    1. Cancer Biology

    NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer

    Shengsheng Zhao, Ji Lin ... Weijian Sun
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Neuroscience

    Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

    Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
    Not revised
    Reviewed Preprint v1
    1. Neuroscience

    Bridging the gap between presynaptic hair cell function and neural sound encoding

    Lina María Jaime Tobón, Tobias Moser
    Synaptic diversity in the ear's inner hair cells significantly empowers sound encoding to enable our processing of sounds across a broad range of intensities.
    1. Neuroscience

    CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells

    David Oestreicher, Shashank Chepurwar ... Tina Pangrsic
    Analysis of Cabp1/2 double knockout phyenotype and rescue by viral delivery of Cabp2 identifies the interplay between two CaBPs to promote sustained synaptic transmission at the inner hair cell synapses.
    1. Cell Biology

    Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis

    Zewei Zhao, Longyun Hu ... Zhonghan Yang
    ADGRA3 signaling promotes adipose thermogenesis via Gs-PKA-CREB, suggesting hesperetin and ADGRA3 overexpression as obesity therapies.