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Latest research

    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

    Susanna Lemmelä et al.
    Elevated growth differentiation factor-15 (GDF15) levels do not appear to be a causal factor in body mass index (BMI) in humans but higher BMI does cause increases in GDF15.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The unmitigated profile of COVID-19 infectiousness

    Ron Sender et al.
    In the absence of COVID-19 mitigation measures, SARS-CoV-2 remains infectious for longer than previously estimated.
    1. Neuroscience

    Prenatal development of neonatal vocalizations

    Darshana Z Narayanan et al.
    Vocal development in marmoset monkeys begins in utero.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy

    Sobhika Agarwala et al.
    Multiple imaging modalities resolved the ultrastructure of single hematopoietic stem cells in their endogenous niche, allowing identification of dopamine beta-hydroxylase positive cells as a functional niche cell type.
    1. Developmental Biology

    Transgenic quails reveal dynamic TCF/β-catenin signaling during avian embryonic development

    Hila Barzilai-Tutsch et al.
    A novel avian transgenic line allows studying the function of Wnt signaling during embryonic development.
    1. Neuroscience

    Expansion and contraction of resource allocation in sensory bottlenecks

    Laura R Edmondson et al.
    A simple efficient coding model predicts complex trade-offs in resource allocation for sensory inputs with heterogeneous receptor densities and activation levels.
    1. Immunology and Inflammation

    Th2 single-cell heterogeneity and clonal distribution at distant sites in helminth-infected mice

    Daniel Radtke et al.
    Th2 cell heterogeneity was revealed by combined transcriptome and T-cell receptor sequencing of single Th2 cells from lung and lymph node of helminth-infected mice and led to identification of a helminth-specific T-cell receptor.
    1. Computational and Systems Biology
    2. Ecology

    Data-driven causal analysis of observational biological time series

    Alex Eric Yuan, Wenying Shou
    Visualizations, simulations, and examples are used to provide an accessible synthesis of the reasoning and assumptions behind commonly used causal discovery approaches.