Browse our latest research

Page 893 of 1,760
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

    Marc A Schureck, Joseph E Darling ... Sanjay A Desai
    A high-resolution structure reveals how the RhopH complex traffics within Plasmodium-infected human erythrocytes to serve divergent, essential functions.
    1. Computational and Systems Biology
    2. Neuroscience

    Bi-channel image registration and deep-learning segmentation (BIRDS) for efficient, versatile 3D mapping of mouse brain

    Xuechun Wang, Weilin Zeng ... Peng Fei
    A dual-channel image registration pipeline combined with deep-learning inference achieves accurate-and-flexible registration/segmentation/mapping of mouse brain.
    1. Cell Biology

    ATP activation of peritubular cells drives testicular sperm transport

    David Fleck, Lina Kenzler ... Marc Spehr
    Purinergic signaling controls mammalian sperm transport.
    1. Computational and Systems Biology

    Drift and termination of spiral waves in optogenetically modified cardiac tissue at sub-threshold illumination

    Sayedeh Hussaini, Vishalini Venkatesan ... Stefan Luther
    Excitability gradients in heart tissue, imposed by structured sub-threshold optogenetic stimulation, induce drift and termination of spiral waves, thus providing an explanation for successful optogenetic defibrillation in small animal hearts.
    1. Developmental Biology
    2. Neuroscience

    Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction

    André Ferreira Castro, Lothar Baltruschat ... Hermann Cuntz
    An optimal wire and function trade-off emerges from noisy growth and stochastic retraction during Drosophila class I ventral posterior dendritic arborisation (c1vpda) dendrite development.
    1. Neuroscience

    Cold-induced hyperphagia requires AgRP neuron activation in mice

    Jennifer D Deem, Chelsea L Faber ... Gregory J Morton
    A combination of neuroscience approaches and indirect calorimetry demonstrate a physiological role for AgRP neurons in cold-induced hyperphagia and strongly suggest temperature is an important regulator of AgRP neuron activity.
    1. Cell Biology

    Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

    Andrea Cipriano, Martina Macino ... Monica Ballarino
    The epigenetic regulation of adult muscle stem cell fate by lnc-Rewind relies on the RNA-mediated recruitment of G9a methyltransferase on the Wnt7b genomic locus.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Collateral sensitivity associated with antibiotic resistance plasmids

    Cristina Herencias, Jerónimo Rodríguez-Beltrán ... Álvaro San Millán
    Acquisition of antibiotic resistance plasmids induces collateral sensitivity to clinically relevant antibiotics in Escherichia coli, paving the way for targeted 'anti-plasmid' therapies able to preferentially eliminate plasmid-carrying bacteria.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    A transcriptomic taxonomy of Drosophila circadian neurons around the clock

    Dingbang Ma, Dariusz Przybylski ... Michael Rosbash
    Drosophila clock neurons manifest remarkable heterogeneity, which might be generally true and help explain why Drosophila has a sophisticated behavioral repertoire despite a tiny brain of about 100,000 neurons.
    1. Neuroscience

    Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

    Willem AM Wybo, Jakob Jordan ... Walter Senn
    A flexible and accurate methodology to fit reduced compartmental models to dendritic morphologies shows that models with very few compartments can capture many dendritic computations.