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Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.

In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.

Gut microbial signatures of domestication parallel those of industrialization, implicating shared ecological drivers.

Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.

In mountain gorillas, as in certain human populations, relationships between group members can act as a social buffer, breaking the link between maternal loss, increased social adversity, and decreased fitness.

Oligodendrocytes with an enhanced ability to withstand cytotoxic stress display an increased capacity to remyelinate demyelination lesions of the CNS in the presence of an inflammatory environment.

Soil microbial diversity loss destabilizes the ability of the soil to function because greater diversity is needed to maintain temporal and functional asynchrony among different microbes.

COVID-19 survivors, who are at risk for vascular complications, would benefit from close monitoring and preventive therapy.

Time-resolved serial femtosecond crystallography revealed retinal kink and early changes in channelrhodopsin, which leads to the ion pore formation.

The binding sites of two distinct TRPC5 inhibitors clemizole and HC-070 are revealed by cryo-EM.