Mapping the central complex

Latest research

1. 1. Neuroscience

   Growth in early infancy drives optimal brain functional connectivity which predicts cognitive flexibility in later childhood

   Chiara Bulgarelli, Anna Blasi ... the BRIGHT Study Team
2. 1. Neuroscience

   Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex

   Astrid Rollenhagen, Akram Sadeghi ... Joachim HR Lübke
3. 1. Computational and Systems Biology

   Pathway activation model for personalized prediction of drug synergy

   Quang Thinh Trac, Yue Huang ... Trung Nghia Vu
4. 1. Structural Biology and Molecular Biophysics

   Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes

   Vikram Dalal, Brandon T Tan ... Wayland WL Cheng
5. 1. Genetics and Genomics
   2. Neuroscience

   Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization Research

   Wei Liu, Zhaoxu Zheng ... Dong Zhang
6. 1. Microbiology and Infectious Disease

   Identifying Genetic Variations in emm89 Streptococcus pyogenes Associated with Severe Invasive Infections

   Masayuki Ono, Masaya Yamaguchi ... Shigetada Kawabata
7. 1. Epidemiology and Global Health

   Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads

   Christian E Gunning, Christopher J Gill, Pejman Rohani
8. 1. Chromosomes and Gene Expression

   MagIC-Cryo-EM, structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

   Yasuhiro Arimura, Hide A Konishi, Hironori Funabiki

   A technique that enables single-particle cryo-EM analysis of targets on a magnetic bead and a particle curation method that helps structural classification of small particles has been developed.
9. 1. Computational and Systems Biology

   Perturbation-response analysis of in silico metabolic dynamics revealed hard-coded responsiveness in the cofactors and network sparsity

   Yusuke Himeoka, Chikara Furusawa

   A computational study reveals that the kinetic models of Escherichia coli metabolism show strong responsiveness to perturbations and that it originates from cofactor dynamics and network sparsity.
10. 1. Neuroscience

    Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca²⁺ ATPase to promote recycling of synaptic vesicles

    Marius Seidenthal, Jasmina Redzovic ... Alexander Gottschalk

    Caenorhabditis elegans FLWR-1/Flower is required for efficient synaptic vesicle recycling and does so through a functional and possibly direct physical interaction with the plasma membrane Ca²⁺ ATPase, MCA-3.