Highlights

  • ERK3 in control

    The kinase ERK3 influences the motility of tumor cells by controlling a previously unknown regulatory pathway.

    Katarzyna Bogucka-Janczi, Gregory Harms ... Krishnaraj Rajalingam
    Research Advance Updated
  • Seeing MHC activation in vivo

    MHC reporter mice can be used to analyse inflammation and neurodegeneration, and to study diseases such as multiple sclerosis.

    Em P Harrington, Riley B Catenacci ... Peter A Calabresi
    Tools and Resources Updated
  • Update on eLife’s new model

    In the first three months, we have seen consistent submissions and positive feedback from authors.

    Inside eLife

Latest research

    1. Neuroscience

    Toward a more informative representation of the fetal–neonatal brain connectome using variational autoencoder

    Jung-Hoon Kim, Josepheen De Asis-Cruz ... Catherine Limperopoulos
    A nonlinear deep generative model can represent fetal–neonatal resting-state functional magnetic resonance imaging better than conventional linear models.
    1. Neuroscience

    Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation

    Ali Mohebi, Val L Collins, Joshua D Berke
    1. Neuroscience

    Role of the postinspiratory complex in regulating swallow-breathing coordination and other laryngeal behaviors

    Alyssa D Huff, Marlusa K Amarante ... Jan-Marino Ramirez
    1. Stem Cells and Regenerative Medicine

    Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors

    Claudia Dell'Amico, Marilyn M Angulo Salavarria ... Marco Onorati
    Microcephaly-associated mutations disrupt microtubule-dependent WDR62 translocation from the Golgi complex to the mitotic spindle poles, impair mitotic progression, and alter neurogenic trajectories in patient induced Pluripotent Stem Cell-derived 2D and 3D models of human neurodevelopment.
    1. Epidemiology and Global Health

    Predictive performance of multi-model ensemble forecasts of COVID-19 across European nations

    Katharine Sherratt, Hugo Gruson ... Sebastian Funk
    A large collaborative project combined many different researchers' forecasts of COVID-19 across Europe, making predictions used in policy more reliable.