About
Editors and people

Editors for Physiology

We aim to review research that employs quantitative experimental and computational approaches to reveal mechanisms driving biological functions across all levels of organisation. We place a strong emphasis on physiological processes at the cellular and molecular scales. Read the latest research in this subject area.

Type

Senior editors

Lu Chen

Stanford University, United States

Lu Chen is a Professor in the Department of Neurosurgery at Stanford University School of Medicine. Her research focuses on understanding the molecular and cellular mechanisms underlying synaptic plasticity and memory engram formation during behavioral learning, and how synapse functions are altered in neurodevelopmental disorders. She received her PhD in Neuroscience from the University of Southern California under the mentorship of Richard Thompson. After a postdoc fellowship in the University of California, San Francisco with Roger Nicoll, she joined the faculty at the University of California, Berkeley in 2003. In 2011, she moved to Stanford University School of Medicine.

Expertise
Neuroscience
Physiology

Research focus
cellular neurophysiology
synaptic physiology
synaptic plasticity
learning
memory
memory engram
hippocampal function
induced human neurons
fragile-X syndrome

Experimental organism
mouse

Competing interests statement
Lu Chen currently receives funding from the National Institutes of Health. She is on the Editorial Board of Current Opinion of Neurobiology and PLOS One. She also serves as an Associate Editor for Frontiers in Synaptic Neuroscience.
Qiang Cui

Boston University, United States

Qiang Cui is a professor of Chemistry at Boston University and also affiliated with the Departments of Physics and Biomedical Engineering. He received a B.S. in Chemical Physics from the University of Science and Technology of China in 1993, and a Ph.D. in Theoretical Chemistry in 1997 from Emory University under the tutelage of Professor Keiji Morokuma. He conducted postodctoral research with Professor Martin Karplus at Harvard University and, in 2001, moved to the University of Wisconsin, Madison, as a faculty member in the Chemistry department. After spending almost 17 wonderful years in Madison, he moved back to Boston in 2018. His current research interests include quantum chemistry and statistical mechanics and their applications to various chemical, biological, and materials problems.

Expertise: Computational biophysics, especially molecular dynamics, hybrid quantum mechanical/molecular mechanics simulations, free energy simulations applied to enzymes, biomolecular machines and lipid membranes.

Expertise
Biochemistry and Chemical Biology
Structural Biology and Molecular Biophysics
Physiology

Research focus
molecular dynamics
hybrid quantum
classical simulations
enzyme catalysis
allostery
protein dynamics
membrane remodeling

Competing interests statement
Qiang Cui currently serves as an associate editor for the Journal of Chemical Theory and Computation (American Chemical Society).
Volker Dötsch

Goethe University, Germany

Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.

Expertise
Structural Biology and Molecular Biophysics
Biochemistry and Chemical Biology
Physiology

Research focus
p53 protein family
cell-free expression and membrane protein structure and function
autophagy

Competing interests statement
Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
Christopher L-H Huang

University of Cambridge, United Kingdom

Prof. Christopher Huang is Professor of Cell Physiology in the University of Cambridge. He read Physiology and Clinical Medicine at the Queen’s College, Oxford on a Florence Heale Scholarship award, and his PhD, at the Physiological Laboratory, Cambridge, on a Medical Research Council award. He was then successively, Assistant Lecturer, Lecturer, Reader in the University of Cambridge. His electrophysiological contributions fall in the areas of skeletal muscle excitation-contraction coupling, cellular ionic homeostasis, central nervous system imaging, and cardiac arrhythmogenic mechanisms in genetic Na⁺, K⁺ and ryanodine receptor channel, and metabolic models, in addition to authoring/editing 7 books/monographs, and 5 journal theme issues. He was awarded the Brian Johnson, Rolleston (Oxford) and Gedge Prizes (Cambridge), and has been editor for Journal of Physiology, Monographs of the Physiological Society, Biological Reviews, Europace, eLife and Biographical Memoirs of Fellows of the Royal Society and Faculty Opinions Integrative Physiology Section Leader. He was Cambridge Philosophical Society President, served on the British Heart Foundation Advisory Council and Fellowships Committee, and is Sino British Fellowship Trustee (UK).

Expertise
Medicine
Physiology

Research focus
cellular muscle electrophysiology
Ca2+ imaging
Na+ channel function and pharmacology
cardiac arrhythmias

Experimental organism
mouse

Competing interests statement
Current funding: British Heart Foundation (UK); BioMarin Ltd. (UK)Editorial Roles: Europace, ELife, Biographical Memoirs of Fellows of the Royal Society; International Journal of Drug Discovery and PharmacologyOthers: Sino-British Fellowship Trust (UK); Faculty Opinions Integrative Physiology Section Leader.Visiting Professorships: Southwest University, Luzhuo, China; University of Surrey, UK.
John Huguenard

Stanford University School of Medicine, United States

John Huguenard is Professor of Neurology and Neurological Sciences at Stanford University School of Medicine, with additional appointments in the Departments of Molecular and Cellular Physiology and Neurosurgery. He joined the faculty in 1994, and served on the executive and steering committees from 2000-2016. He was director of the Stanford Neurosciences PhD program from 2006-2013, and of the NIH T32 supported Stanford Postdoctoral Epilepsy Training Program from 2004 to the present. His work is on neurophysiology of voltage- and ligand-gated ion channels in neural circuits related to neuropsychiatric diseases such as epilepsy and autism spectrum disorders. A particular focus is mechanisms of action of antiepileptic drugs, and development of modern therapeutic interventions such as on demand optogenetics. His work is multidisciplinary including in vitro electrophysiology, genetic models, computational neuroscience, multiphoton microscopy, image analysis, and in vivo imaging and extracellular neurophysiology. He is a Fellow of the American Association for the Advancement of Science. He has received the research career award from the American Epilepsy Society and has served on its board.

Expertise
Neuroscience
Physiology

Research focus
thalamocortical epileptic network
epilepsy
cortical microcircuitry
ion channels

Experimental organism
mouse

Competing interests statement
John Huguenard is employed by Stanford University. He receives research funding from the National Institutes of Health and the Simons Foundation. He is a Fellow of the American Association for the Advancement of Science. He serves actively on the editorial boards of Experimental Neurology and Journal of Computational Neuroscience.
Merritt Maduke

Stanford University School of Medicine, United States

Merritt Maduke is an Associate Professor of Molecular & Cellular Physiology and co-director of the Neurosciences Interdisciplinary Graduate Program at Stanford University School of Medicine. She received her PhD in Chemistry from the University of California, San Diego and did postdoctoral training at Brandeis University with Professor Chris Miller. Her research at Stanford is centered on the biophysics of ion channels and transporters, with the overarching goal of understanding molecular mechanisms within the context of physiological functions. She also applies her mechanistic approach in the field of ultrasound neuromodulation. She was awarded the Society of General Physiologist’s Cranefield Award for her research on ion channels (2008) and served as the Society’s President from 2018-2019.

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Biochemistry and Chemical Biology
Physiology

Research focus
ion channel and transporter molecular mechanisms
ion channel and transporter physiology
ion channel and transporter pharmacology
ultrasound neuromodulation

Experimental organism
E. coli
mouse
rat

Competing interests statement
Merritt Maduke is employed by Stanford University and receives research funding from the National Institutes of Health and Stanford Innovative Medicine Accelerator. She has served on the BPNS and BBM study sections at the NIH and as ad hoc member of additional panels. She serves on the editorial boards of the Biophysical Journal and The Journal of General Physiology and is a founding curator for Biophysics Colab.
Satyajit Rath

National Institute of Immunology, New Delhi, India

Satyajit Rath was trained as a physician and a pathologist in Pune and Mumbai, India. He has worked on various issues related to the mechanisms involved in the development and functioning of the immune system since the nineteen-eighties, initially in post-doctoral stints across the world and then as a faculty member at the National Institute of Immunology (NII) in New Delhi, and as an adjunct faculty member at the Translational Health Science and Technology Institute, Faridabad, India and the Christian Medical College, Vellore, India. After formal retirement, he has also held honorary positions as the Agharkar Chair at the Agharkar Research Institute, Pune, India, and as a professor emeritus at the Indian Institute of Science Education and Research (IISER), Pune, India. Satyajit also works on science-and-society policies as well as science education and outreach with both government agencies and civil society groups.

Expertise
Immunology and Inflammation
Physiology

Research focus
immune physiology
lymphocyte development
lymphocyte responses
macrophage activation
immunity in disease

Competing interests statement
Research support for Satyajit's group over the years has come mainly from agencies of the government of India. He serves and has served as a member of scientific advisory committees/ councils as well as of management boards of a number of life science institutions in India as well as funding agencies of the government of India. He is currently editorially associated with Frontiers in Immunology, Clinical and Translational Immunology, and DIALOGUE: Science, Scientists, and Society. He is also associated in advisory capacities with small biotech companies such as Ahammune Biosciences Private Limited, Pune, India, Curadev Pharma Private Limited, NOIDA, India, and Mynvax Private Limited, Bangalore, India.
Dolores Shoback

University of California, San Francisco, United States

Dr Dolores Shoback cares for patients with a variety of disorders related to the endocrine system, focusing particularly on metabolic bone disease, parathyroid disorders and osteoporosis. She also directs UCSF's physician training program in diabetes, endocrinology and metabolism.

Shoback's research interests include metabolic bone disease, the calcium-sensing receptor and parathyroid hormone.

Shoback completed her undergraduate studies at the University of Pennsylvania. She earned her MD from the Johns Hopkins School of Medicine and completed a residency in internal medicine at the Johns Hopkins Hospital. She completed a fellowship in endocrinology at Brigham and Women's Hospital.

Expertise
Medicine
Physiology

Research focus
endocrinology
hormones
bone metabolism
calcium
mineral
parathyroid
vitamin D

Experimental organism
human
mouse

Competing interests statement
Dr Shoback is currently funded by the NIH.
Kenton J Swartz

National Institute of Neurological Disorders and Stroke, NIH, United States

Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Biochemistry and Chemical Biology
Physiology

Research focus
ion channel structure
ion channel mechanisms
ion channel physiology
ion channel pharmacology

Experimental organism
mouse

Competing interests statement
Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.

Reviewing editors

Yousef Abu-Amer

Washington University School of Medicine, United States

Expertise
Cell Biology
Immunology and Inflammation
Medicine
Physiology

Research focus
osteolysis
osteoclast
osteoarthritis
osteoimmunology
inflammatory arthritis
RANKL
Anurag Agrawal

CSIR Institute of Genomics and Integrative Biology, India

Expertise
Medicine
Physiology

Research focus
asthma
respiratory diseases

Experimental organism
human
mouse
Sameh Ali

Children's Cancer Hospital Egypt, Egypt

Expertise
Biochemistry and Chemical Biology
Cancer Biology
Cell Biology
Immunology and Inflammation
Neuroscience
Structural Biology and Molecular Biophysics
Physiology

Research focus
metabolism
mitochondria
redox biology
reactive oxygen species
membrane biophysics
inflammation
aging
oncology
Toby W Allen

RMIT University, Australia

Expertise
Structural Biology and Molecular Biophysics
Physics of Living Systems
Neuroscience
Physiology

Research focus
computational biophysics
molecular dynamics
free-energy calculations
ion channels
ion permeation
membranes
Ariel Amir

Harvard University, United States

Expertise
Physics of Living Systems
Physiology

Research focus
mathematical modeling
stochastic processes
microbial growth
cell size control
gene expression
microbial evolution
phenotypic variability
Rozalyn M Anderson

University of Wisconsin-Madison, United States

Expertise
Cell Biology
Medicine
Physiology

Research focus
aging
metabolism
caloric restriction
Michelle Antoine

National Institute on Alcohol Abuse and Alcoholism (NIAAA), United States

Expertise
Neuroscience
Physiology

Research focus
neural circuits
autism
ADHD
E-I balance
striatum
synaptic transmission
neurodevelopment
epilepsy
Hossein Ardehali

University of Arizona, United States

Expertise
Medicine
Biochemistry and Chemical Biology
Physiology

Research focus
mitochondria
iron
glucose metabolism
mRNA-binding proteins
hexokinases
metabolism
cardiac biology
Hua Bai

Iowa State University, United States

Expertise
Cell Biology
Developmental Biology
Genetics and Genomics
Physiology

Research focus
human cell culture

Experimental organism
Drosophila
Soumen Basak

National Institute of Immunology, India

Expertise
Immunology and Inflammation
Physiology

Research focus
inflammation
signalling
metabolism
colon
barrier
musculoskeletal
myalgia/arthralgia
virus
Patricia Bassereau

Institut Curie, France

Expertise
Cell Biology
Physics of Living Systems
Structural Biology and Molecular Biophysics
Physiology

Research focus
physics of cells
membrane biophysics
mechanobiology
intracellular traffic
endocytosis
adhesion
cellular protrusions
biomimetic membranes
Kurt Beam

University of Colorado Anschutz Medical Campus, United States

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Physics of Living Systems
Physiology

Research focus
excitation-contraction coupling in skeletal muscle
voltage-gated calcium channels
calcium release channels
Hugo J Bellen

Baylor College of Medicine, United States

Expertise
Neuroscience
Developmental Biology
Genetics and Genomics
Physiology

Research focus
neurobiology
human neurological disease
Alzheimer's disease
Parkinson's disease
diagnosis of human genetic diseases
fly technology
CRIMIC
MiMIC

Experimental organism
D. melanogaster
mouse
Gabrielle T Belz

The Walter and Eliza Hall Institute of Medical Research, Australia

Expertise
Immunology and Inflammation
Physiology

Research focus
innate immunity
immune protection
adaptive immunity
transcriptional regulation
T cell memory
innate immune cells
pathogen infection
viral infection
immune cell differentiation

Experimental organism
mouse
Bérénice A Benayoun

University of Southern California, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation
Physiology

Research focus
aging
macrophages
inflammation
sex differences
menopause
sex hormones

Experimental organism
mouse
African turquoise killifish
Anton M Bennett

Yale University, United States

Expertise
Cell Biology
Biochemistry and Chemical Biology
Cancer Biology
Physiology

Research focus
cell signalling
metabolism
protein tyrosine phosphorylation
protein tyrosine kinases
protein tyrosine phosphatases
Jimena Berni

University of Sussex, United Kingdom

Expertise
Neuroscience
Developmental Biology
Physiology

Research focus
locomotion
developmental biology
central pattern generators
neurogenetics
neurobiology
genetic basis of behavior

Experimental organism
Drosophila
Audrey M Bernstein

State University of New York Upstate Medical University, United States

Expertise
Cell Biology
Medicine
Stem Cells and Regenerative Medicine
Physiology

Research focus
cornea
scarring
fibrosis
glaucoma
integrins
myofibroblast
Roberto Bottini

University of Trento, Italy

Expertise
Neuroscience
Physiology

Research focus
memory
cognitive maps
conceptual knowledge
brain plasticity
spatial navigation
neuroimaging
fMRI
Jeffrey J Brault

Indiana University, United States

Expertise
Cell Biology
Biochemistry and Chemical Biology
Physiology

Research focus
skeletal muscle
bioenergetics
mitochondria
atrophy
ATP

Experimental organism
mouse
Axel T Brunger

Stanford University, United States

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Physiology

Research focus
neurotransmission
membrane fusion
X-ray crystallography
electron microscopy
macromolecular computer simulation

Experimental organism
mouse
Christoph Buettner

Rutgers Robert Wood Johnson Medical School, United States

Expertise
Medicine
Physiology

Research focus
metabolism
diabetes
Ernesto Canalis

UConn Health, United States

Expertise
Medicine
Cell Biology
Physiology

Research focus
osteoblasts
osteoclasts
mouse genetics
rare diseases
notch
Jay J Cao

United States Department of Agriculture, United States

Expertise
Medicine
Physiology

Research focus
bone metabolism
obesity
Megan R Carey

Champalimaud Foundation, Portugal

Expertise
Neuroscience
Physiology

Research focus
computational and systems neuroscience
cerebellum
neural circuits
locomotion
sensorimotor systems
motor learning

Experimental organism
mouse
Anne E Carlson

University of Pittsburgh, United States

Expertise
Developmental Biology
Structural Biology and Molecular Biophysics
Physiology

Research focus
fertilization
ion channel regulation
biophysics
sperm
calcium
eggs
zinc
TMEM16A
Marlon Cerf

South African Medical Research Council, South Africa

Expertise
Cell Biology
Medicine
Physiology

Research focus
diabetes
cardiovascular disease
SDGs
fetal programming
obesity
Moses V Chao

New York University Langone Medical Center, United States

Expertise
Neuroscience
Physiology

Research focus
trophic factors
receptor signal transduction
growth factors
Xin Chen

Johns Hopkins University, United States

Expertise
Developmental Biology
Chromosomes and Gene Expression
Physiology

Research focus
germ cells
stem cells
asymmetric cell division
histones
epigenetics
transcription

Experimental organism
C. elegans
D. melanogaster
Iacopo Chiodini

Ospedale Niguarda Ca' Granda, Italy

Expertise
Medicine
Physiology

Research focus
adrenal gland
bone metabolism
osteoporosis
calcium metabolism
bone fragility
Sandipan Chowdhury

University of Iowa, United States

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
physiology
biophysics
Rosana Collepardo

University of Cambridge, United Kingdom

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
epigenetic phenomena
DNA structure
gene expression
molecular modeling
Seth J Corey

Cleveland Clinic, United States

Expertise
Cancer Biology
Medicine
Physiology

Research focus
myeloid malignancies
inherited or acquired bone marrow failure
neutrophils
platelets zebrafish
cancer evolution
proteostasis
Michael Czech

University of Massachusetts Medical School, United States

Expertise
Cell Biology
Physiology

Research focus
insulin
metabolism
lipid-protein interactions
signal transduction
membranes
adipose
obesity
insulin resistance
diabetes

Experimental organism
human
mouse
Laura R Delgui

National Scientific and Technical Research Council, Argentina

Expertise
Cell Biology
Microbiology and Infectious Disease
Structural Biology and Molecular Biophysics
Physiology

Research focus
virus-host cell interactions
membranes
molecular biology
cellular biology
structural biology
biophysics
molecular dynamics
Dion K Dickman

University of Southern California, United States

Expertise
Neuroscience
Physiology

Research focus
synapse
plasticity
homeostasis
neuromuscular junction
glutamate

Experimental organism
D. melanogaster
Jun Ding

Stanford University, United States

Expertise
Neuroscience
Physiology

Research focus
neural circuits
motor learning
motor control
Parkinson's disease
synaptic transmission
synaptic plasticity
dendrites
spine
dopamine

Experimental organism
mouse
Rafael Fernández-Chacon

Instituto de Biomedicina de Sevilla (IBiS), Spain

Expertise
Neuroscience
Cell Biology
Physiology

Research focus
synapse
neurotransmitter release
synaptic maintenance
electrophysiology
neurodegeneration
synaptic vesicle cycle
neuronal ceroid lipofuscinosis

Experimental organism
mouse
Aaron Frank

Arrakis Therapeutics, United States

Expertise
Structural Biology and Molecular Biophysics
Biochemistry and Chemical Biology
Physiology

Research focus
molecular modeling
biophysics
structural biology
computation
RNA biochemistry
RNA structural biology
Dipyaman Ganguly

Indian Institute of Chemical Biology, India

Expertise
Immunology and Inflammation
Medicine
Cell Biology
Microbiology and Infectious Disease
Physiology

Research focus
cellular immunology
inflammation
dendritic cells
cell migration
endocytosis
autoimmune diseases
infectious diseases
Luigi Gennari

University of Siena, Italy

Expertise
Medicine
Physiology

Research focus
metabolic bone disease
Paget's disease of bone
endocrinology
Gregory G Germino

National Institute of Diabetes and Digestive and Kidney Diseases, United States

Expertise
Medicine
Genetics and Genomics
Physiology

Research focus
nephrology
genetic renal disease
internal medicine
ciliopathies

Experimental organism
mouse
rat
human
Arjumand Ghazi

University of Pittsburgh School of Medicine, United States

Expertise
Developmental Biology
Genetics and Genomics
Immunology and Inflammation
Stem Cells and Regenerative Medicine
Physiology

Research focus
aging
geroscience
reproductive aging
longevity
healthspan
oocytes
innate immunity
inflammation
proteostasis

Experimental organism
C. elegans
Drosophila melanogaster
mouse
Florent Ginhoux

Agency for Science Technology and Research, Singapore

Expertise
Immunology and Inflammation
Neuroscience
Stem Cells and Regenerative Medicine
Physiology

Research focus
dendritic cells
monocytes
macrophages
development
hematopoiesis

Experimental organism
human
mouse
Marcel Goldschen-Ohm

University of Texas at Austin, United States

Expertise
Neuroscience
Structural Biology and Molecular Biophysics
Physiology

Research focus
ion channel structure and mechanisms
single molecule dynamics
single molecule fluorescence
patch-clamp electrophysiology
ligand binding
Frederik Graw

Heidelberg University, Germany

Expertise
Immunology and Inflammation
Computational and Systems Biology
Microbiology and Infectious Disease
Physiology

Research focus
mathematical modelling
theoretical immunology
host-pathogen interactions
viral spread
infection dynamics

Experimental organism
mouse
viruses
Christine Grienberger

Brandeis University, United States

Expertise
Neuroscience
Physiology

Research focus
learning and memory
synaptic plasticity
neurodegenerative diseases
dendritic integration
Shozeb Haider

University College London, United Kingdom

Expertise
Medicine
Structural Biology and Molecular Biophysics
Computational and Systems Biology
Microbiology and Infectious Disease
Physiology

Research focus
X-ray crystallography
molecular dynamics simulations
allostery
structure-based drug design
structural bioinformatics
computational chemistry
nucleic acids
rare diseases
Donald Hamelberg

Georgia State University, United States

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
molecular dynamics
classical simulations
protein dynamics
protein allostery
enzyme catalysis
Long time scale dynamics
Weiping Han

Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore

Expertise
Neuroscience
Cell Biology
Physiology

Research focus
diabetes
enzymes
metabolism
obesity
secretion
exocytosis
Brandon Harvey

NIDA/NIH, Intramural Research Program, United States

Expertise
Cell Biology
Immunology and Inflammation
Neuroscience
Physiology

Research focus
neuroinflammation
ER stress
UPR
ER calcium
KDEL receptor
manf
stroke

Experimental organism
rat
mouse
human cells
Margaret S Ho

National Yang Ming Chiao Tung University, Taiwan

Expertise
Neuroscience
Cell Biology
Physiology

Research focus
glia
neurodegenerative disease
protein degradation
neuron-glia interactions
inflammation
innate behaviors

Experimental organism
Drosophila
mouse
Heedeok Hong

Michigan State University, United States

Expertise
Structural Biology and Molecular Biophysics
Biochemistry and Chemical Biology
Physiology

Research focus
membrane proteins
membrane protein folding
membrane protein stability
rhomboid proteases
ATP-dependent proteolysis
AAA+
GlpG
FtsH
Valerie Horsley

Yale University, United States

Expertise
Cell Biology
Developmental Biology
Stem Cells and Regenerative Medicine
Physiology

Research focus
epithelial stem cells
adipocyte stem cells
adipose tissue
epithelial-mesenchymal interactions
mechanical regulation of tissues
tissue regeneration
Maneesha S Inamdar

Jawaharlal Nehru Centre for Advanced Scientific Research, India

Expertise
Developmental Biology
Cell Biology
Stem Cells and Regenerative Medicine
Physiology

Research focus
pluripotent stem cells
hematopoiesis
vascular
organelles
mitochondria
vesicular trafficking
cytoskeleton
protein sorting
Leon D. Islas

Universidad Nacional Autónoma de México, Mexico

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
molecular computation
membrane proteins
ion channels
fluorescence
models
Aya Ito-Ishida

Keio University School of Medicine, Japan

Expertise
Neuroscience
Physiology

Research focus
synapse formation
circuit development
cerebellum
neurodevelopmental disorders
Rett syndrome

Experimental organism
mouse
Alicia Izquierdo

University of California, Los Angeles, USA, United States

Expertise
Neuroscience
Physiology

Research focus
behavioral and systems neuroscience
frontal cortex
reward learning
value learning
behavioral flexibility
value-based decision making
Andres Jara-Oseguera

University of Texas at Austin, United States

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Physiology

Research focus
ion channels
Transient Receptor Potential (TRP) channels
membrane transport proteins
nociception
voltage-activated channels
cellular excitability
pain-signaling
Johnny Kim

TRON gGmbH, Germany

Expertise
Developmental Biology
Stem Cells and Regenerative Medicine
Physiology

Research focus
stem cells
regeneration
cardiovascular biomedicine
muscle biology
reprogramming
aging
totipotency
pluripotency
cell therapy
gene therapy

Experimental organism
mouse
human
Genevieve Konopka

The University of Texas Southwestern Medical Center, United States

Expertise
Neuroscience
Genetics and Genomics
Evolutionary Biology
Physiology

Research focus
comparative genomics
autism
schizophrenia
neurogenomics
cognition
language
molecular neuroscience

Experimental organism
human
mouse
David M Kramer

Michigan State University, United States

Expertise
Biochemistry and Chemical Biology
Plant Biology
Physics of Living Systems
Computational and Systems Biology
Physiology

Research focus
photosynthesis
bioenergetics
electron and proton transfer
computation
phenotyping
phenomics
Karsten Kruse

University of Geneva, Switzerland

Expertise
Biochemistry and Chemical Biology
Physics of Living Systems
Physiology

Research focus
cell migration
cell signalling
theoretical biology
molecular evolution
Tomohiro Kurosaki

Osaka University, Japan

Expertise
Immunology and Inflammation
Physiology

Research focus
acquired immunity
vaccine development
B cell
antibody
T cell
autoimmune diseases

Experimental organism
human
mouse
Dudley W Lamming

University of Wisconsin-Madison, United States

Expertise
Medicine
Biochemistry and Chemical Biology
Physiology

Research focus
aging
physiology
dietary restriction
amino acids
diabetes
obesity
metabolism
protein

Experimental organism
mouse
Bruno Lemaitre

Ecole Polytechnique Fédérale de Lausanne, Switzerland

Expertise
Immunology and Inflammation
Physiology

Research focus
innate immunity
gut
Drosophila
pattern-recognition
entomopathogens
insect endosymbionts

Experimental organism
D. melanogaster
Elena Levashina

Max Planck Institute for Infection Biology, Germany

Expertise
Microbiology and Infectious Disease
Physiology

Research focus
malaria ecology
mosquito immune system
Anopheles gambiae

Experimental organism
P. falciparum
Richard Lewis

Stanford University School of Medicine, United States

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
ion channels
calcium signaling
Peng Liu

Icahn School of Medicine at Mount Sinai, United States

Expertise
Medicine
Cell Biology
Physiology

Research focus
obesity
aging
osteoporosis
Adipose Biology
Bone Biology (osteoblasts and osteoclasts)
Mychael V Lourenco

Federal University of Rio de Janeiro, Brazil

Expertise
Cell Biology
Medicine
Neuroscience
Physiology

Research focus
Alzheimer's disease
synaptic plasticity
translational control
hormones
memory
neurodegeneration
biomarkers
Kay F Macleod

University of Chicago, United States

Expertise
Cell Biology
Cancer Biology
Physiology

Research focus
autophagy
mitochondria
pancreatic cancer
breast cancer
liver homeostasis
tumor metabolism

Experimental organism
mouse
human
Fabrizio Marinelli

Medical College of Wisconsin, United States

Expertise
Structural Biology and Molecular Biophysics
Biochemistry and Chemical Biology
Physiology

Research focus
computational biophysics
molecular dynamics
membrane proteins
membrane transporters
ion channels
membrane remodeling
integrative structural biology
computational methods development
Pascal Martin

Institut Curie, France

Expertise
Neuroscience
Physics of Living Systems
Physiology

Research focus
active mechanical processes
hair cells of the inner ear
molecular motors and the cytoskeleton
oscillations
mechanosensitivity
frequency selectivity
in vitro reconstituted motor systems

Experimental organism
rat
Xenopus
Gherardo Mazziotti

Humanitas University of Milan, Italy

Expertise
Medicine
Physiology

Research focus
endocrinology
pituitary disease
growth hormone
thyroid
FSH
thyroid diseases
secondary osteoporosis
insulin-like growth factor-1
ACTH
cortisol
prolactin
TSH
PTH
Zoe A McElligott

University of North Carolina at Chapel Hill, United States

Expertise
Neuroscience
Physiology

Research focus
optogenetics
psychiatric illness
whole-cell electrophysiology
chemogenetics
caspase ablation
behavioral assays
Alphee Michelot

Mechanobiology Institute, Singapore

Expertise
Cell Biology
Physics of Living Systems
Physiology

Research focus
cytoskeleton
actin dynamics
motility
endocytosis
cytokinesis
actin mechanics
energy conversion
force transduction

Experimental organism
S. cerevisiae
Subburaman Mohan

Loma Linda University, United States

Expertise
Medicine
Genetics and Genomics
Physiology

Research focus
bone biology
endochondral bone formation
insulin-like growth factors
osteoporosis
osteoarthritis
skeletal development

Experimental organism
human
Marcelo A Mori

State University of Campinas, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation
Physiology

Research focus
aging
metabolism
obesity
adipose tissue
microRNAs
endocrinology
integrative physiology
Tomohiro Morio

Tokyo Medical and Dental University, Japan

Expertise
Immunology and Inflammation
Medicine
Physiology

Research focus
primary immunodeficiency
pediatrics
cell therapy
monogenic disorder
iPS cells
Tina Mukherjee

Institute for Stem Cell Biology and Regenerative Medicine (inStem), India

Expertise
Stem Cells and Regenerative Medicine
Developmental Biology
Physiology

Research focus
metabolism
myeloid development and function
stem cells and development
neuro-immune crosstalk

Experimental organism
drosophila
mouse
mosquitos
Armita Nourmohammad

University of Washington, United States

Expertise
Computational and Systems Biology
Evolutionary Biology
Physics of Living Systems
Immunology and Inflammation
Physiology

Research focus
population genetics
computational immunology
adaptive immunity
statistical physics
deep mutational scanning
information theory
statistical inference
gene expression evolution

Experimental organism
D. melanogaster
human
viruses
Anna Panchenko

Queen's University, Canada

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Cancer Biology
Physiology

Research focus
molecular modeling
bioinformatics
machine learning
molecular dynamics simulations
cancer mutations
chromosome and nucleosome dynamics
Benjamin L Parker

University of Melbourne, Australia

Expertise
Cell Biology
Computational and Systems Biology
Biochemistry and Chemical Biology
Physiology

Research focus
proteomics
signal transduction
metabolism
skeletal muscle
exercise
insulin resistance
phosphorylation
protein post-translational modifications
Adrien Peyrache

McGill University, United States

Expertise
Neuroscience
Physiology

Research focus
spatial navigation
sleep
memory consolidation
replay
neural coding

Experimental organism
mouse
Kate Poole

UNSW Sydney, Australia

Expertise
Cell Biology
Structural Biology and Molecular Biophysics
Physiology

Research focus
mechanobiology
mechanosensitive ion channels
patch-clamp electrophysiology
ion channels
microgravity
cellular force sensing
atomic force microscopy
Douglas Portman

University of Rochester, United States

Expertise
Developmental Biology
Neuroscience
Physiology

Research focus
neurogenetics
behavioral genetics
behavioral plasticity
hypothamalus sex differences
neuronal development

Experimental organism
C. elegans
Murali Prakriya

Northwestern University, United States

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Physiology

Research focus
cell imaging
cellular electrophysiology
calcium signaling
ion channels
neurobiology
cell physiology

Experimental organism
mouse
Benjamin L Prosser

University of Pennsylvania Perelman School of Medicine, United States

Expertise
Cell Biology
Physics of Living Systems
Chromosomes and Gene Expression
Physiology

Research focus
cardiac function
muscle
cardiomyocytes
mechanotransduction
cytoskeleton
microtubules
sarcomere
Jalees Rehman

University of Illinois at Chicago, United States

Expertise
Cell Biology
Genetics and Genomics
Immunology and Inflammation
Medicine
Stem Cells and Regenerative Medicine
Physiology

Research focus
vascular biology
macrophage biology
inflammation
transcriptomics
single cell analysis
lung biology
cell regeneration
Jeremy Reiter

University of California, San Francisco, United States

Expertise
Cell Biology
Developmental Biology
Stem Cells and Regenerative Medicine
Physiology

Research focus
cilia
Fred Rieke

HHMI, University of Washington, United States

Expertise
Neuroscience
Physiology

Research focus
non-human primates
computational neuroscience
biophysics

Experimental organism
mouse
Julien Roche

Iowa State University, United States

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
protein folding
intrinsically disordered proteins
solution NMR spectroscopy
Lee L Rubin

Harvard Stem Cell Institute, Harvard University, United States

Expertise
Stem Cells and Regenerative Medicine
Physiology

Research focus
neurodegenerative disease
neuromuscular diseases
brain aging

Experimental organism
human (iPSCs)
mouse
Mishaela R Rubin

Columbia University Medical Center, United States

Expertise
Medicine
Physiology

Research focus
diabetes
parathyroid
osteoporosis
Sarah Russell

Peter MacCallum Cancer Centre, Australia

Expertise
Cell Biology
Developmental Biology
Immunology and Inflammation
Physiology

Research focus
cell fate determination
T cells
cell polarity
synapse
asymmetric cell division
Scribble

Experimental organism
mouse
Tomás J Ryan

Trinity College Dublin, Ireland

Expertise
Neuroscience
Physiology

Research focus
memory
engram
behavior
evolution
learning
neuroimmunology
development
instinct
Jon T Sack

University of California, Davis, United States

Expertise
Structural Biology and Molecular Biophysics
Neuroscience
Physiology

Research focus
ion channels
voltage gating
voltage clamp electrophysiology
ligand binding
allostery
rate theory modeling
thermodynamics
Shimon Sakaguchi

Osaka University, Japan

Expertise
Immunology and Inflammation
Physiology

Research focus
B cells
immune tolerance
autoimmune disease
tumor immunity
Irene Salinas

University of New Mexico, United States

Expertise
Immunology and Inflammation
Neuroscience
Evolutionary Biology
Microbiology and Infectious Disease
Physiology

Research focus
mucosal immunology
neuroimmunology
host-microbe interactions
evolutionary immunology
Alejandro San Martín

Centro de Estudios Científicos and Universidad San Sebastián, Chile

Expertise
Biochemistry and Chemical Biology
Cancer Biology
Cell Biology
Physiology

Research focus
imaging
metabolism
FRET
single-fluorophore
single-cell
cell physiology
optogenetics
Apurva Sarin

Institute for Stem Cell Science and Regenerative Medicine, India

Expertise
Cell Biology
Immunology and Inflammation
Physiology

Research focus
apoptosis
Notch1
signal transduction
T cells

Experimental organism
mouse
Helen Scharfman

New York University Langone Medical Center, United States

Expertise
Neuroscience
Physiology

Research focus
hippocampus
neuronal excitability
neurogenesis
brain-derived neurotrophic factor
neuroendocrinology
epilepsy
Alzheimer’s disease
Shimon Schuldiner

The Hebrew University of Jerusalem, Israel

Expertise
Biochemistry and Chemical Biology
Microbiology and Infectious Disease
Physiology

Research focus
ion-coupled transporters
neurotransporters
multidrug transporters
vesicular transporters
antibiotic resistance
bioenergetics
microbial physiology
membrane proteins
Annalisa Scimemi

University at Albany, State University of New York, United States

Expertise
Neuroscience
Physiology

Research focus
synaptic physiology
synaptic plasticity
synaptic integration
neurotransmitter transporters
astrocytes
modeling
hippocampus
basal ganglia
neurological disorders
Pierre Sens

Institut Curie, France

Expertise
Physics of Living Systems
Physiology

Research focus
statistical physics
soft matter
membrane
cell mechanics
cell motility
organelles
Jiwon Shim

Seoul National University of Science and Technology, South Korea

Expertise
Cell Biology
Developmental Biology
Genetics and Genomics
Immunology and Inflammation
Physiology

Research focus
hematopoiesis
innate immunity
hemocyte
development
signaling
inter-organ communication

Experimental organism
D. melanogaster
Show-Ling Shyng

Oregon Health and Science University, United States

Expertise
Biochemistry and Chemical Biology
Cell Biology
Structural Biology and Molecular Biophysics
Physiology

Research focus
ion channels
protein structure-function
electrophysiology
pharmacology
intracellular trafficking
signal transduction
chaperones
islet biology
Inna Slutsky

Tel Aviv University, Israel

Expertise
Neuroscience
Physiology

Research focus
cellular and circuit-level neuroscience
neuronal homeostasis
synaptic plasticity
synaptic transmission
Alzheimer's disease

Experimental organism
rodents
N. Ravi Sundaresan

Indian Institute of Science, India

Expertise
Cell Biology
Medicine
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Stem Cells and Regenerative Medicine
Physiology

Research focus
reversable acetylation
ADP-ribosylation
cellular senescence and aging
sirtuins
cardiac and skeletal muscle diseases
fibrosis

Experimental organism
human
mouse
rat
Kiyoshi Takeda

Osaka University, Japan

Expertise
Immunology and Inflammation
Medicine
Physiology

Research focus
mucosal immunology
inflammatory bowel disease
intestinal immunity
intestinal environmental factors
intestinal epithelial cells
Lipi Thukral

CSIR-Institute of Genomics and Integrative Biology, India

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
computational structural biology
molecular dynamics simulations
protein-lipid interactions
vesicles
membranes
autophagy
structural genomics
protein crowding
spike protein
Mohamed Trebak

University of Pittsburgh School of Medicine, United States

Expertise
Structural Biology and Molecular Biophysics
Cell Biology
Biochemistry and Chemical Biology
Physiology

Research focus
calcium channels
receptor signalling
ion channel regulation
vascular remodeling
smooth muscle
John C Tuthill

University of Washington, United States

Expertise
Neuroscience
Physics of Living Systems
Physiology

Research focus
sensory coding
motor control
locomotion
animal behavior
proprioception
weird insects

Experimental organism
drosophila
chionea
Mei Wan

Johns Hopkins University School of Medicine, United States

Expertise
Medicine
Cell Biology
Physiology

Research focus
bone remodeling
osteoarthritis
osteoblasts
osteoclast
cellular senescence
mesenchymal stem cells
progenitor cells
Huili Wang

Hefei University of Technology, China

Expertise
Neuroscience
Physiology

Research focus
synaptic plasticity
learning
memory
engram cell
neural circuits
gene-environment interactions
epigenetic regulation
Andrew West

Duke University, United States

Expertise
Neuroscience
Physiology

Research focus
neurological disorders
neurodegeneration

Experimental organism
human
rodents
Urbain Weyemi

National Cancer Institute, National Institutes of Health, United States

Expertise
Cancer Biology
Physiology

Research focus
cancer metabolism
genomic stability
redox biology
reactive oxygen species
cancer therapy
mitochondrial homeostasis
R Luke Wiseman

Scripps Research, United States

Expertise
Biochemistry and Chemical Biology
Cell Biology
Physiology

Research focus
proteostasis
stress-responsive signaling
unfolded protein response
protein secretion
mitochondria regulation
small molecule development
Keqiang Ye

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China

Expertise
Medicine
Cancer Biology
Biochemistry and Chemical Biology
Neuroscience
Physiology

Research focus
neuroscience
molecular cytobiology
cancer biology
neurodegenerative disease

Experimental organism
mouse
Simon Yona

The Hebrew University of Jerusalem, Israel

Expertise
Immunology and Inflammation
Physiology

Research focus
monocytes
macrophages
dendritic cells
inflammation

Experimental organism
mouse
human
Mark L Zeidel

Beth Israel Deaconess Medical Center, United States

Expertise
Medicine
Physiology

Research focus
kidney disease
bladder disease
Anja Zeigerer

Helmholtz Zentrum München, Germany

Expertise
Cell Biology
Medicine
Physiology

Research focus
type 2 diabetes
membrane trafficking
mitochondria
cellular and systemic metabolism
liver physiology
MASLD
endo-lysosomal system
Bin Zhang

Massachusetts Institute of Technology, United States

Expertise
Physics of Living Systems
Structural Biology and Molecular Biophysics
Physiology

Research focus
computational biophysics
molecular dynamics
chromatin organization
biomolecular condensates
genome folding
coarse graining
Lejla Zubcevic

University of Kansas Medical Center, United States

Expertise
Structural Biology and Molecular Biophysics
Physiology

Research focus
ion channels
membrane transport
structural biology
Juan Carlos Zúñiga-Pflücker

University of Toronto, Sunnybrook Research Institute, Canada

Expertise
Immunology and Inflammation
Stem Cells and Regenerative Medicine
Physiology

Research focus
developmental immunology
thymus
T cell development
notch signaling
lymphopoiesis
preTCR signaling
gamma/delta T cell differentiation

Experimental organism
human
mouse