1. Evolutionary Biology
Download icon

Experimental Evolution: A sticky solution

  1. David Gresham  Is a corresponding author
  1. New York University, United States
Insight
Cite this article as: eLife 2013;2:e00655 doi: 10.7554/eLife.00655
1 figure

Figures

The budding yeast S. cerevisiae feeds on sucrose that it metabolizes outside the cell using the enzyme invertase, which it secretes into its surroundings.

The breakdown products—glucose and fructose—are then imported into the cell and used to drive growth. If sucrose is in short supply and the density of single cells is low, the cells cannot capture enough of the glucose and fructose to initiate growth (upper panel). Under these conditions, mutations that cause the cells to form undifferentiated multicellular clumps (lower panel) confer an advantage, by increasing the local concentration of glucose and fructose available to cells. Selection for these mutations may lead ultimately to the evolution of multicellularity.

FIGURE CREDIT: IMAGES: [JOHN KOSCHWANEZ].

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Download citations (links to download the citations from this article in formats compatible with various reference manager tools)

Open citations (links to open the citations from this article in various online reference manager services)