1. Biochemistry and Chemical Biology
  2. Genetics and Genomics
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Epigenetics: Making the most of methylation

  1. Michiel Vermeulen  Is a corresponding author
  1. University Medical Center Utrecht, Netherlands
Cite this article as: eLife 2013;2:e01387 doi: 10.7554/eLife.01387
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Some human transcription factors can bind to both methylated and non-methylated DNA sequences. Hu et al. examined the ability of 17 human transcription factors to bind to 150 different DNA motifs containing methylated or non-methylated CpG islands. Each row represents one transcription factor. For each motif, some transcription factors bound only to the methylated version (red), some to only the non-methylated version (blue); some to both methylated and non-methylated versions (green), and some to neither (grey). From Figure 2a in Hu et al., 2013.

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