TY - JOUR TI - Visual processing of informative multipoint correlations arises primarily in V2 AU - Yu, Yunguo AU - Schmid, Anita M AU - Victor, Jonathan D A2 - Behrens, Timothy VL - 4 PY - 2015 DA - 2015/04/27 SP - e06604 C1 - eLife 2015;4:e06604 DO - 10.7554/eLife.06604 UR - https://doi.org/10.7554/eLife.06604 AB - Using the visual system as a model, we recently showed that the efficient coding principle accounted for the allocation of computational resources in central sensory processing: when sampling an image is the main limitation, resources are devoted to compute the statistical features that are the most variable, and therefore the most informative (eLife 2014;3:e03722. DOI: 10.7554/eLife.03722 Hermundstad et al., 2014). Building on these results, we use single-unit recordings in the macaque monkey to determine where these computations—sensitivity to specific multipoint correlations—occur. We find that these computations take place in visual area V2, primarily in its supragranular layers. The demonstration that V2 neurons are sensitive to the multipoint correlations that are informative about natural images provides a common computational underpinning for diverse but well-recognized aspects of neural processing in V2, including its sensitivity to corners, junctions, illusory contours, figure/ground, and ‘naturalness.’ KW - macaque KW - vision KW - extrastriate cortex JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -