TY - JOUR TI - An extended retinotopic map of mouse cortex AU - Zhuang, Jun AU - Ng, Lydia AU - Williams, Derric AU - Valley, Matthew AU - Li, Yang AU - Garrett, Marina AU - Waters, Jack A2 - Kleinfeld, David VL - 6 PY - 2017 DA - 2017/01/06 SP - e18372 C1 - eLife 2017;6:e18372 DO - 10.7554/eLife.18372 UR - https://doi.org/10.7554/eLife.18372 AB - Visual perception and behavior are mediated by cortical areas that have been distinguished using architectonic and retinotopic criteria. We employed fluorescence imaging and GCaMP6 reporter mice to generate retinotopic maps, revealing additional regions of retinotopic organization that extend into barrel and retrosplenial cortices. Aligning retinotopic maps to architectonic borders, we found a mismatch in border location, indicating that architectonic borders are not aligned with the retinotopic transition at the vertical meridian. We also assessed the representation of visual space within each region, finding that four visual areas bordering V1 (LM, P, PM and RL) display complementary representations, with overlap primarily at the central hemifield. Our results extend our understanding of the organization of mouse cortex to include up to 16 distinct retinotopically organized regions. KW - cortex KW - topographic map KW - visual map JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -