TY - JOUR TI - Partial loss of genes might open therapeutic window AU - Liu, Bo AU - Abdel-Wahab, Omar VL - 6 PY - 2017 DA - 2017/03/17 SP - e25996 C1 - eLife 2017;6:e25996 DO - 10.7554/eLife.25996 UR - https://doi.org/10.7554/eLife.25996 AB - The loss of genes that encode RNA splicing factors weakens cancer cells in a way that could be exploited by new approaches to treatment. KW - copy number alterations KW - spliceosome KW - SF3B1 KW - target identification and validation KW - CYCLOPS genes KW - cancer therapeutics JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -