TY - JOUR TI - Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio) AU - Cong, Lin AU - Wang, Zeguan AU - Chai, Yuming AU - Hang, Wei AU - Shang, Chunfeng AU - Yang, Wenbin AU - Bai, Lu AU - Du, Jiulin AU - Wang, Kai AU - Wen, Quan A2 - Calabrese, Ronald L VL - 6 PY - 2017 DA - 2017/09/20 SP - e28158 C1 - eLife 2017;6:e28158 DO - 10.7554/eLife.28158 UR - https://doi.org/10.7554/eLife.28158 AB - The internal brain dynamics that link sensation and action are arguably better studied during natural animal behaviors. Here, we report on a novel volume imaging and 3D tracking technique that monitors whole brain neural activity in freely swimming larval zebrafish (Danio rerio). We demonstrated the capability of our system through functional imaging of neural activity during visually evoked and prey capture behaviors in larval zebrafish. KW - freely behaving larval zebrafish KW - whole brain Imaging KW - 3D tracking system KW - light field microscope KW - prey capture behavior JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -