1. Neuroscience
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Functional MRI: Making connections in the brain

  1. Alex TL Leong
  2. Ed X Wu  Is a corresponding author
  1. University of Hong Kong, China
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Cite this article as: eLife 2017;6:e32064 doi: 10.7554/eLife.32064
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Combining resting-state functional MRI measurements of blood oxygenation and calcium recordings of spontaneous neural activity in the rat brain.

The blue trace shows slow oscillations in a calcium recording of spontaneous neural activity in the primary somatosensory cortex; the trace shown here is approximately 80 seconds long. Schwalm et al. converted such traces into binary signals (black) and then used this binary signal to analyze the results of resting-state functional MRI measurements on the whole brain. This analysis revealed that the slow oscillations generate a resting-state fMRI connectivity network (red and yellow) that extends cortex-wide from the primary somatosensory cortex (S1) to the primary visual cortex (V1).

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