Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

  1. Zhening Zhang
  2. Wenguang G Liang
  3. Lucas J Bailey
  4. Yong Zi Tan
  5. Hui Wei
  6. Andrew Wang
  7. Mara Farcasanu
  8. Virgil A Woods
  9. Lauren A McCord
  10. David Lee
  11. Weifeng Shang
  12. Rebecca Deprez-Poulain
  13. Benoit Deprez
  14. David R Liu
  15. Akiko Koide
  16. Shohei Koide
  17. Anthony A Kossiakoff
  18. Sheng Li  Is a corresponding author
  19. Bridget Carragher  Is a corresponding author
  20. Clinton S Potter  Is a corresponding author
  21. Wei-Jen Tang  Is a corresponding author
  1. New York Structural Biology Center, United States
  2. The University of Chicago, United States
  3. University of California, San Diego, United States
  4. Argonne National Laboratory, United States
  5. Université de Lille, France
  6. Harvard University, United States
  7. New York University, United States
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  1. Zhening Zhang
  2. Wenguang G Liang
  3. Lucas J Bailey
  4. Yong Zi Tan
  5. Hui Wei
  6. Andrew Wang
  7. Mara Farcasanu
  8. Virgil A Woods
  9. Lauren A McCord
  10. David Lee
  11. Weifeng Shang
  12. Rebecca Deprez-Poulain
  13. Benoit Deprez
  14. David R Liu
  15. Akiko Koide
  16. Shohei Koide
  17. Anthony A Kossiakoff
  18. Sheng Li
  19. Bridget Carragher
  20. Clinton S Potter
  21. Wei-Jen Tang
(2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
eLife 7:e33572.
https://doi.org/10.7554/eLife.33572