TY - JOUR TI - Perceptual processing in the ventral visual stream requires area TE but not rhinal cortex AU - Eldridge, Mark AG AU - Matsumoto, Narihisa AU - Wittig, John H, Jnr AU - Masseau, Evan C AU - Saunders, Richard C AU - Richmond, Barry J A2 - Davachi, Lila A2 - Marder, Eve VL - 7 PY - 2018 DA - 2018/10/12 SP - e36310 C1 - eLife 2018;7:e36310 DO - 10.7554/eLife.36310 UR - https://doi.org/10.7554/eLife.36310 AB - There is an on-going debate over whether area TE, or the anatomically adjacent rhinal cortex, is the final stage of visual object processing. Both regions have been implicated in visual perception, but their involvement in non-perceptual functions, such as short-term memory, hinders clear-cut interpretation. Here, using a two-interval forced choice task without a short-term memory demand, we find that after bilateral removal of area TE, monkeys trained to categorize images based on perceptual similarity (morphs between dogs and cats), are, on the initial viewing, badly impaired when given a new set of images. They improve markedly with a small amount of practice but nonetheless remain moderately impaired indefinitely. The monkeys with bilateral removal of rhinal cortex are, under all conditions, indistinguishable from unoperated controls. We conclude that the final stage of the integration of visual perceptual information into object percepts in the ventral visual stream occurs in area TE. KW - perception KW - vison KW - temporal lobe KW - ventral visual stream KW - inferotemporal KW - perirhinal cortex JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -