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Correction: Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice

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Cite this article as: eLife 2018;7:e38909 doi: 10.7554/eLife.38909

Main text

Villani C, Sacchetti G, Bagnati R, Passoni A, Fusco F, Carli M, Invernizzi RW. 2016. Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice. eLife 5:e22409. doi: 10.7554/eLife.22409.

Published 28, November 2016

Recently, a reader noticed that concentration units for brain levels of 24S-OHC in the legend to Table 2 were not correct. We discovered that in preparing Table 2 and Table 2—source data 1, we inadvertently assigned the wrong units to 24S-OHC concentration (ng/g instead of ng/mg).

Below, the original text of Table 2 legend:

“Table 2. Effect of Mecp2 deletion on brain levels of 24S-OHC.

Brain levels of 24S-OHC, expressed as ng/g of tissue, were measured in 28 (PND28) and 56 (PND56) day old Mecp2-null and WT male mice and in PND177 Mecp2+/- females and WT mice. Food was removed from cage 6 hr before sacrifice. Data are means ± SEM of 5–6 mice per group. **p<0.01, ***p<0.001 vs. WT (Student’s t-test)”

and the corrected version:

“Table 2. Effect of Mecp2 deletion on brain levels of 24S-OHC.

Brain levels of 24S-OHC, expressed as ng/mg of tissue, were measured in 28 (PND28) and 56 (PND56) day old Mecp2-null and WT male mice and in PND177 Mecp2+/- females and WT mice. Food was removed from cage 6 hr before sacrifice. Data are means ± SEM of 5–6 mice per group. **p<0.01, ***p<0.001 vs. WT (Student’s t-test)”

Concentration units in Table 2—Source data 1 have been corrected accordingly. The correction does not change any of the conclusions that we drew from these data. We apologize for any confusions this oversight may have caused.

Article and author information

Author details

  1. Giuseppina Sacchetti

  2. Renzo Bagnati

  3. Alice Passoni

  4. Federica Fusco

  5. Mirjana Carli

Publication history

  1. Version of Record published: June 29, 2018 (version 1)

Copyright

© 2018, Villani et al.

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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