Correction: Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice

Villani C, Sacchetti G, Bagnati R, Passoni A, Fusco F, Carli M, Invernizzi RW. 2016. Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice. eLife 5:e22409. doi: 10.7554/eLife.22409.

Published 28, November 2016

Recently, a reader noticed that concentration units for brain levels of 24S-OHC in the legend to Table 2 were not correct. We discovered that in preparing Table 2 and Table 2—source data 1, we inadvertently assigned the wrong units to 24S-OHC concentration (ng/g instead of ng/mg).

Below, the original text of Table 2 legend:

“Table 2. Effect of Mecp2 deletion on brain levels of 24S-OHC.

Brain levels of 24S-OHC, expressed as ng/g of tissue, were measured in 28 (PND28) and 56 (PND56) day old Mecp2-null and WT male mice and in PND177 Mecp2^+/- females and WT mice. Food was removed from cage 6 hr before sacrifice. Data are means ± SEM of 5–6 mice per group. **p<0.01, ***p<0.001 vs. WT (Student’s t-test)”

and the corrected version:

“Table 2. Effect of Mecp2 deletion on brain levels of 24S-OHC.

Brain levels of 24S-OHC, expressed as ng/mg of tissue, were measured in 28 (PND28) and 56 (PND56) day old Mecp2-null and WT male mice and in PND177 Mecp2^+/- females and WT mice. Food was removed from cage 6 hr before sacrifice. Data are means ± SEM of 5–6 mice per group. **p<0.01, ***p<0.001 vs. WT (Student’s t-test)”

Concentration units in Table 2—Source data 1 have been corrected accordingly. The correction does not change any of the conclusions that we drew from these data. We apologize for any confusions this oversight may have caused.