1. Neuroscience
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Sex Difference: What does cannabis do to the brain before birth?

  1. Stefano Musardo  Is a corresponding author
  2. Camilla Bellone  Is a corresponding author
  1. University of Geneva, Switzerland
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Cite this article as: eLife 2018;7:e41229 doi: 10.7554/eLife.41229
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Effects of prenatal exposure to cannabinoids on male and female rats.

Being in contact with cannabinoids in the womb leads to changes in the medial prefrontal cortex (PFC) of adult male rats (blue), for example causing prefrontal cortex pyramidal neurons to fire more easily (spikes). These animals interact less with their peers and do not play as much. Female rats (pink) with the same life history are not affected by prenatal cannabinoid exposure.

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