1. Computational and Systems Biology
  2. Genetics and Genomics
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Life Expectancy: Advancing the aging biology toolkit

  1. Troy K Coody
  2. Adam L Hughes  Is a corresponding author
  1. University of Utah School of Medicine, United States
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Cite this article as: eLife 2018;7:e42976 doi: 10.7554/eLife.42976
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Key technological advances in yeast-aging research.

The development of new tools to study replicative aging in yeast has been crucial to overcome the limitations imposed by the scarcity of old yeast cells in a growing cell population. This timeline depicts broadly adopted technologies that have enabled both single-cell and large-scale measurements using biochemical or genetic approaches to characterize the molecular mechanisms of aging; see main text for more details. Large circles represent mother yeast cells; small circles represent daughter yeast cells; small circles with a red cross represent daughter cells prevented from maturing.

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