PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis

  1. Norihiro Yamaguchi
  2. Ethan M Weinberg
  3. Alexander Nguyen
  4. Maria V Liberti
  5. Hani Goodarzi
  6. Yelena Y Janjigian
  7. Philip B Paty
  8. Leonard B Saltz
  9. T Peter Kingham
  10. Jia Min Loo
  11. Elisa de Stanchina
  12. Sohail F Tavazoie  Is a corresponding author
  1. The Rockefeller University, United States
  2. Memorial Sloan-Kettering Cancer Center, United States
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  1. Norihiro Yamaguchi
  2. Ethan M Weinberg
  3. Alexander Nguyen
  4. Maria V Liberti
  5. Hani Goodarzi
  6. Yelena Y Janjigian
  7. Philip B Paty
  8. Leonard B Saltz
  9. T Peter Kingham
  10. Jia Min Loo
  11. Elisa de Stanchina
  12. Sohail F Tavazoie
(2019)
PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis
eLife 8:e52135.
https://doi.org/10.7554/eLife.52135