1. Biochemistry and Chemical Biology
  2. Microbiology and Infectious Disease

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

  1. Ali Alghamdi
  2. Jane C Munday
  3. Gustavo Daniel Campagnaro
  4. Dominik Gurvic
  5. Fredrik Svensson
  6. Chinyere E Okpara
  7. Arvind Kumar
  8. Juan Quintana
  9. Maria Esther Martin Abril
  10. Patrik Milić
  11. Laura Watson
  12. Daniel Paape
  13. Luca Settimo
  14. Anna Dimitriou
  15. Joanna Wielinska
  16. Graeme Smart
  17. Laura F Anderson
  18. Christopher M Woodley
  19. Siu Pui Ying Kelly
  20. Hasan MS Ibrahim
  21. Fabian Hulpia
  22. Mohammed I Al-Salabi
  23. Anthonius A Eze
  24. Teresa Sprenger
  25. Ibrahim A Teka
  26. Simon Gudin
  27. Simone Weyand
  28. Mark C Field
  29. Christophe Dardonville
  30. Richard R Tidwell
  31. Mark Carrington
  32. Paul M O'Neill
  33. David W Boykin
  34. Ulrich Zachariae
  35. Harry P De Koning  Is a corresponding author
  1. University of Glasgow, United Kingdom
  2. University of Dundee, United Kingdom
  3. IOTA Pharmaceuticals Ltd, United Kingdom
  4. University of Liverpool, United Kingdom
  5. Georgia State University, United States
  6. University of Ghent, Belgium
  7. University of Cambridge, United Kingdom
  8. CSIC, Spain
  9. University of North Carolina at Chapel Hill, United States
https://doi.org/10.7554/eLife.56416
Share this article
Cite this article
  1. Ali Alghamdi
  2. Jane C Munday
  3. Gustavo Daniel Campagnaro
  4. Dominik Gurvic
  5. Fredrik Svensson
  6. Chinyere E Okpara
  7. Arvind Kumar
  8. Juan Quintana
  9. Maria Esther Martin Abril
  10. Patrik Milić
  11. Laura Watson
  12. Daniel Paape
  13. Luca Settimo
  14. Anna Dimitriou
  15. Joanna Wielinska
  16. Graeme Smart
  17. Laura F Anderson
  18. Christopher M Woodley
  19. Siu Pui Ying Kelly
  20. Hasan MS Ibrahim
  21. Fabian Hulpia
  22. Mohammed I Al-Salabi
  23. Anthonius A Eze
  24. Teresa Sprenger
  25. Ibrahim A Teka
  26. Simon Gudin
  27. Simone Weyand
  28. Mark C Field
  29. Christophe Dardonville
  30. Richard R Tidwell
  31. Mark Carrington
  32. Paul M O'Neill
  33. David W Boykin
  34. Ulrich Zachariae
  35. Harry P De Koning
(2020)
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
eLife 9:e56416.
https://doi.org/10.7554/eLife.56416
  2. Download BibTeX
  3. Download .RIS
1 additional file

Additional files

All additional files

Any figure supplements, source code, source data, videos or supplementary files associated with this article are contained within this zip.

https://cdn.elifesciences.org/articles/56416/elife-56416-supp-v2.zip

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Open citations (links to open the citations from this article in various online reference manager services)

Cite this article (links to download the citations from this article in formats compatible with various reference manager tools)

  1. Ali Alghamdi
  2. Jane C Munday
  3. Gustavo Daniel Campagnaro
  4. Dominik Gurvic
  5. Fredrik Svensson
  6. Chinyere E Okpara
  7. Arvind Kumar
  8. Juan Quintana
  9. Maria Esther Martin Abril
  10. Patrik Milić
  11. Laura Watson
  12. Daniel Paape
  13. Luca Settimo
  14. Anna Dimitriou
  15. Joanna Wielinska
  16. Graeme Smart
  17. Laura F Anderson
  18. Christopher M Woodley
  19. Siu Pui Ying Kelly
  20. Hasan MS Ibrahim
  21. Fabian Hulpia
  22. Mohammed I Al-Salabi
  23. Anthonius A Eze
  24. Teresa Sprenger
  25. Ibrahim A Teka
  26. Simon Gudin
  27. Simone Weyand
  28. Mark C Field
  29. Christophe Dardonville
  30. Richard R Tidwell
  31. Mark Carrington
  32. Paul M O'Neill
  33. David W Boykin
  34. Ulrich Zachariae
  35. Harry P De Koning
(2020)
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
eLife 9:e56416.
https://doi.org/10.7554/eLife.56416