Atlas priors for interfaces between structures are combined to the MRI data, regularized via probability diffusion and topology correction, and the final structure posteriors are jointly estimated by region growing.
Scores for the left and right side are computed separately and then combined into box-and-whisker plots.
MASSP priors were not derived from the contrasts, but transferred via a spatial mapping of the quantitative MRI intensities from AHEAD subjects.
Each matrix show the average Dice overlap (top), dilated Dice overlap (middle), and average surface distance (bottom) for using one age group as prior (’train’) to parcellate another age group (’test’).
Circles show individual data points, linear regression is indicated by a straight line, and 95% confidence interval is given as the shaded area. Pearson correlation coefficients are indicated when significant (p-value<0.01).
Manual delineations for the 17 structures of interest are overlaid on all images.