Processing of motion-boundary orientation in macaque V2

  1. Heng Ma
  2. Pengcheng Li
  3. Jiaming Hu
  4. Xingya Cai
  5. Qianling Song
  6. Haidong D Lu  Is a corresponding author
  1. Beijing Normal University, China

Abstract

Human and non-human primates are good at identifying an object based on its motion, a task that is believed to be carried out by the ventral visual pathway. However, the neural mechanisms underlying such ability remains unclear. We trained macaque monkeys to do orientation discrimination for motion-boundaries (MB) and recorded neuronal response in area V2 with microelectrode arrays. We found 10.9% of V2 neurons exhibited robust orientation-selectivity to MBs, and their responses correlated with monkeys' orientation-discrimination performances. Furthermore, the responses of V2 direction-selective neurons recorded at the same time showed correlated activity with MB neurons for particular MB stimuli, suggesting that these motion-sensitive neurons made specific functional contributions to MB discrimination tasks. Our findings support the view that V2 plays a critical role in MB analysis and may achieve this through a neural circuit within area V2.

Data availability

Data and codes are available in Mendeley dataset.http://dx.doi.org/10.17632/fjy37kc8pd.3

The following data sets were generated

Article and author information

Author details

  1. Heng Ma

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0002-0322-278X
  2. Pengcheng Li

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Competing interests
    The authors declare that no competing interests exist.
  3. Jiaming Hu

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0002-5306-445X
  4. Xingya Cai

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-7829-3833
  5. Qianling Song

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-9177-7429
  6. Haidong D Lu

    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    For correspondence
    haidong@bnu.edu.cn
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-1739-9508

Funding

National Natural Science Foundation of China (31530029)

  • Haidong D Lu

National Natural Science Foundation of China (31625012)

  • Haidong D Lu

National Natural Science Foundation of China (31371111)

  • Haidong D Lu

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Ethics

Animal experimentation: Four hemispheres from two adult male macaque monkeys (Macaca mulatta) were used in this study. All procedures were performed in accordance with the National Institutes of Health Guidelines and were approved by the Institutional Animal Care and Use Committee of the Beijing Normal University (protocol number: IACUC(BNU)-NKCNL2013-13).

Reviewing Editor

  1. Kristine Krug, University of Oxford, United Kingdom

Publication history

  1. Received: July 22, 2020
  2. Accepted: March 24, 2021
  3. Accepted Manuscript published: March 24, 2021 (version 1)
  4. Version of Record published: April 7, 2021 (version 2)
  5. Version of Record updated: April 13, 2021 (version 3)

Copyright

© 2021, Ma et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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  1. Heng Ma
  2. Pengcheng Li
  3. Jiaming Hu
  4. Xingya Cai
  5. Qianling Song
  6. Haidong D Lu
(2021)
Processing of motion-boundary orientation in macaque V2
eLife 10:e61317.
https://doi.org/10.7554/eLife.61317

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