Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction

  1. Laura Le Pelletier
  2. Matthieu Mantecon
  3. Jennifer Gorwood
  4. Martine Auclair
  5. Roberta Foresti
  6. Roberto Motterlini
  7. Mireille Laforge
  8. Michael Atlan
  9. Bruno Fève
  10. Jacqueline Capeau
  11. Claire Lagathu  Is a corresponding author
  12. Veronique Bereziat  Is a corresponding author
  1. Sorbonne Université, INSERM UMR_S 938, RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), France
  2. University Paris-Est Créteil, INSERM, IMRB, France
  3. CNRS, INSERM UMRS_1124, Faculté des sciences fondamentales et biomédicales, Université de Paris, France
  4. Sorbonne Université, INSERM UMR_S 938, RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), AP-HP Tenon Hospital Department of Plastic Surgery, F-75020 Paris, France
  5. Sorbonne Université, INSERM UMR_S 938, RHU CARMMA, Institute of Cardiometabolism and Nutrition (ICAN), AP-HP, Saint Antoine Hospital, Department of Endocrinology, PRISIS, F-75012 Paris, France
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  1. Laura Le Pelletier
  2. Matthieu Mantecon
  3. Jennifer Gorwood
  4. Martine Auclair
  5. Roberta Foresti
  6. Roberto Motterlini
  7. Mireille Laforge
  8. Michael Atlan
  9. Bruno Fève
  10. Jacqueline Capeau
  11. Claire Lagathu
  12. Veronique Bereziat
(2021)
Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction
eLife 10:e62635.
https://doi.org/10.7554/eLife.62635