Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin

  1. Nithin Sam Ravi
  2. Beeke Wienert
  3. Stacia K Wyman
  4. Henry William Bell
  5. Anila George
  6. Gokulnath Mahalingam
  7. Jonathan T Vu
  8. Kirti Prasad
  9. Bhanu Prasad Bandlamudi
  10. Nivedhitha Devaraju
  11. Vignesh Rajendiran
  12. Nazar Syedbasha
  13. Aswin Anand Pai
  14. Yukio Nakamura
  15. Ryo Kurita
  16. Muthuraman Narayanasamy
  17. Poonkuzhali Balasubramanian
  18. Saravanabhavan Thangavel
  19. Srujan Marepally
  20. Shaji R Velayudhan
  21. Alok Srivastava
  22. Mark A DeWitt
  23. Merlin Crossley
  24. Jacob E Corn
  25. Kumarasamypet Murugesan Mohankumar  Is a corresponding author
  1. Christian Medical College, India
  2. Gladstone Institutes, United States
  3. University of California, Berkeley, United States
  4. University of New South Wales, Australia
  5. Christian Medical College & Hospital, India
  6. RIKEN BioResource Center, Japan
  7. Japanese Red Cross Society, Japan, Japan
  8. University of California, Los Angeles, United States
  9. ETH Zurich, Switzerland
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  1. Nithin Sam Ravi
  2. Beeke Wienert
  3. Stacia K Wyman
  4. Henry William Bell
  5. Anila George
  6. Gokulnath Mahalingam
  7. Jonathan T Vu
  8. Kirti Prasad
  9. Bhanu Prasad Bandlamudi
  10. Nivedhitha Devaraju
  11. Vignesh Rajendiran
  12. Nazar Syedbasha
  13. Aswin Anand Pai
  14. Yukio Nakamura
  15. Ryo Kurita
  16. Muthuraman Narayanasamy
  17. Poonkuzhali Balasubramanian
  18. Saravanabhavan Thangavel
  19. Srujan Marepally
  20. Shaji R Velayudhan
  21. Alok Srivastava
  22. Mark A DeWitt
  23. Merlin Crossley
  24. Jacob E Corn
  25. Kumarasamypet Murugesan Mohankumar
(2022)
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
eLife 11:e65421.
https://doi.org/10.7554/eLife.65421