TY - JOUR TI - Vision, challenges and opportunities for a Plant Cell Atlas AU - Plant Cell Atlas Consortium AU - Jha, Suryatapa Ghosh AU - Borowsky, Alexander T AU - Cole, Benjamin J AU - Fahlgren, Noah AU - Farmer, Andrew AU - Huang, Shao-shan Carol AU - Karia, Purva AU - Libault, Marc AU - Provart, Nicholas J AU - Rice, Selena L AU - Saura-Sanchez, Maite AU - Agarwal, Pinky AU - Ahkami, Amir H AU - Anderton, Christopher R AU - Briggs, Steven P AU - Brophy, Jennifer AN AU - Denolf, Peter AU - Di Costanzo, Luigi F AU - Exposito-Alonso, Moises AU - Giacomello, Stefania AU - Gomez-Cano, Fabio AU - Kaufmann, Kerstin AU - Ko, Dae Kwan AU - Kumar, Sagar AU - Malkovskiy, Andrey V AU - Nakayama, Naomi AU - Obata, Toshihiro AU - Otegui, Marisa S AU - Palfalvi, Gergo AU - Quezada-Rodríguez, Elsa H AU - Singh, Rajveer AU - Uhrig, R Glen AU - Waese, Jamie AU - Van Wijk, Klaas AU - Wright, R Clay AU - Ehrhardt, David W AU - Birnbaum, Kenneth D AU - Rhee, Seung Y A2 - Rodgers, Peter A2 - Loissel, Elsa VL - 10 PY - 2021 DA - 2021/09/07 SP - e66877 C1 - eLife 2021;10:e66877 DO - 10.7554/eLife.66877 UR - https://doi.org/10.7554/eLife.66877 AB - With growing populations and pressing environmental problems, future economies will be increasingly plant-based. Now is the time to reimagine plant science as a critical component of fundamental science, agriculture, environmental stewardship, energy, technology and healthcare. This effort requires a conceptual and technological framework to identify and map all cell types, and to comprehensively annotate the localization and organization of molecules at cellular and tissue levels. This framework, called the Plant Cell Atlas (PCA), will be critical for understanding and engineering plant development, physiology and environmental responses. A workshop was convened to discuss the purpose and utility of such an initiative, resulting in a roadmap that acknowledges the current knowledge gaps and technical challenges, and underscores how the PCA initiative can help to overcome them. KW - location-to-function KW - Plant Cell Atlas KW - translational research KW - 4D imaging KW - single-cell omics KW - science forum JF - eLife SN - 2050-084X PB - eLife Sciences Publications, Ltd ER -