Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis

  1. Lukas P Feilen
  2. Shu-Yu Chen
  3. Akio Fukumori
  4. Regina Feederle
  5. Martin Zacharias
  6. Harald Steiner  Is a corresponding author
  1. German Center for Neurodegenerative Diseases, Germany
  2. Technical University of Munich, Germany
  3. Osaka Medical and Pharmaceutical University, Japan
  4. Helmholtz Zentrum München, Germany
  5. Ludwig-Maximilians-Universität München, Germany
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  1. Lukas P Feilen
  2. Shu-Yu Chen
  3. Akio Fukumori
  4. Regina Feederle
  5. Martin Zacharias
  6. Harald Steiner
(2022)
Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis
eLife 11:e76090.
https://doi.org/10.7554/eLife.76090