1. Cancer Biology
  2. Structural Biology and Molecular Biophysics

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers

  1. Jean-Philippe Defour
  2. Emilie Leroy
  3. Sharmila Dass
  4. Thomas Balligand
  5. Gabriel Levy
  6. Ian C Brett
  7. Nicolas Papadopoulos
  8. Céline Mouton
  9. Lidvine Genet
  10. Christian Pecquet
  11. Judith Staerk
  12. Steven O Smith  Is a corresponding author
  13. Stefan N Constantinescu  Is a corresponding author
  1. Université Catholique de Louvain, Belgium
  2. Stony Brook University, United States
https://doi.org/10.7554/eLife.81521
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  1. Jean-Philippe Defour
  2. Emilie Leroy
  3. Sharmila Dass
  4. Thomas Balligand
  5. Gabriel Levy
  6. Ian C Brett
  7. Nicolas Papadopoulos
  8. Céline Mouton
  9. Lidvine Genet
  10. Christian Pecquet
  11. Judith Staerk
  12. Steven O Smith
  13. Stefan N Constantinescu
(2023)
Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers
eLife 12:e81521.
https://doi.org/10.7554/eLife.81521
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  1. Jean-Philippe Defour
  2. Emilie Leroy
  3. Sharmila Dass
  4. Thomas Balligand
  5. Gabriel Levy
  6. Ian C Brett
  7. Nicolas Papadopoulos
  8. Céline Mouton
  9. Lidvine Genet
  10. Christian Pecquet
  11. Judith Staerk
  12. Steven O Smith
  13. Stefan N Constantinescu
(2023)
Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers
eLife 12:e81521.
https://doi.org/10.7554/eLife.81521

Share this article

https://doi.org/10.7554/eLife.81521