Browse our Research Articles

Page 200 of 1,403
    1. Computational and Systems Biology

    Analysis of NIH K99/R00 awards and the career progression of awardees

    Nicole C Woitowich, Sarah R Hengel ... Daniel J Tyrrell
    There is a significant disadvantage to receive a major grant (i.e., R01) for K99/R00 awardees that are women, those at lower funded institutions, and those with lower career mobility.
    1. Chromosomes and Gene Expression

    Regulation of chromatin architecture by transcription factor binding

    Stephanie Portillo-Ledesma, Suckwoo Chung ... Tamar Schlick
    The binding of transcription factors to mesoscale chromatin fibers leads to microdomains whose features are dependent on the linker DNA length, linker histone density, and tail acetylation levels.
    1. Neuroscience

    Acetylcholine modulates the precision of prediction error in the auditory cortex

    David Pérez-González, Ana Belén Lao-Rodríguez ... Manuel S Malmierca
    Acetylcholine plays a multifold role in modulating neuronal mismatch in auditory cortex, affecting the precision of prediction error signaling and gating prediction errors to hierarchically higher processing levels.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Genetic basis of Arabidopsis thaliana responses to infection by naïve and adapted isolates of turnip mosaic virus

    Anamarija Butkovic, Thomas James Ellis ... Santiago F Elena
    Arabidopsis lines were screened for resistance to TuMV, identifying a region on chromosome 2 linked to necrosis that includes an antiviral gene.
    1. Genetics and Genomics
    2. Medicine

    Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition

    Dylan C Sarver, Jean Garcia-Diaz ... G William Wong
    Mice lacking Tmem263 are dwarfs, and this phenotype is associated with reduced hepatic growth hormone (GH) receptor expression, a deficit in GH-induced signaling, and low insulin-like growth factor 1 level.
    1. Neuroscience

    Transcranial focused ultrasound to human rIFG improves response inhibition through modulation of the P300 onset latency

    Justin M Fine, Archana S Mysore ... Marco Santello
    Ultrasonic neurostimulation in humans can manipulate response inhibition related behavior and neural activity.
    1. Neuroscience

    What happens to the inhibitory control functions of the right inferior frontal cortex when this area is dominant for language?

    Esteban Villar-Rodríguez, Cristina Cano-Melle ... César Avila
    A complementary relationship exists between the hemispheric lateralization of inhibitory control (typically right) and speech (typically left), as observed in typically and atypically lateralized left-handed individuals.
    1. Stem Cells and Regenerative Medicine

    An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis

    J Barney Bryson, Alexandra Kourgiantaki ... Linda Greensmith
    Stem-cell-based neural replacement, in combination with optogenetic stimulation, could represent a translationally viable therapeutic strategy to overcome atrophy and paralysis of targeted muscles in people living with amyotrophic lateral sclerosis.
    1. Neuroscience

    Dynamics and maintenance of categorical responses in primary auditory cortex during task engagement

    Rupesh K Chillale, Shihab Shamma ... Yves Boubenec
    Primary auditory cortex shows population-level correlates of sound categorization, with categorical patterns emerging during sound presentation and task engagement leading to asymmetrical representation of stimuli, indicating an early involvement in stimulus categorization.
    1. Neuroscience

    A generative model of electrophysiological brain responses to stimulation

    Diego Vidaurre
    Genephys is a generative model for dissecting the different aspects that compound our neural responses to perceptual stimulation, identifying which aspects remain stable and which ones vary across experimental repetitions.