Browse our Research Articles

Page 201 of 1,403
    1. Neuroscience

    14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention

    Qiuling Liu, Hua Yang ... Zhisheng Ji
    14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury in mice.
    1. Evolutionary Biology

    Evolution of the gene regulatory network of body axis by enhancer hijacking in amphioxus

    Chenggang Shi, Shuang Chen ... Guang Li
    The gene regulatory network of Nodal signaling, underpinning body axes patterning, was evolved specifically in cephalochordate lineage.
    1. Immunology and Inflammation

    Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS

    Daniel C Akuma, Kimberly A Wodzanowski ... Igor E Brodsky
    Caspase-11 catalytic activity and autoprocessing play key roles upstream rather than downstream of its assembly into higher-order inflammasome complexes in response to cytosolic bacterial lipopolysaccharide.
    1. Neuroscience

    Neuroendocrine gene expression coupling of interoceptive bacterial food cues to foraging behavior of C. elegans

    Sonia A Boor, Joshua D Meisel, Dennis H Kim
    Distinct interoceptive and gustatory bacterial food cues converge to control neuroendocrine gene expression in two neurons, which modulates and is correlated with internal states driving feeding versus foraging behavior.
    1. Neuroscience

    Serial attentional resource allocation during parallel feature value tracking

    Christian Merkel, Luise Burgmann ... Jens-Max Hopf
    The strong limitation of human subjects in tracking two color streams simultaneously as they independently traverse color space can be attributed to attention alternating slowly and sequentially between streams.
    1. Computational and Systems Biology
    2. Neuroscience

    Neuroimaging and behavioral evidence that violent video games exert no negative effect on human empathy for pain and emotional reactivity to violence

    Lukas Leopold Lengersdorff, Isabella C Wagner ... Claus Lamm
    After playing violent video games for 7 hr over the course of 2 weeks, human male participants show neither signs of decreased empathy for the pain of another person nor of decreased responsivity to violent images.
    1. Developmental Biology

    Differential susceptibility of male and female germ cells to glucocorticoid-mediated signaling

    Steven A Cincotta, Nainoa Richardson ... Diana J Laird
    Although developing oocytes and sperm of mice both harbor the glucocorticoid receptor, fetal oocytes are resistant to differing levels of gluocorcorticoid stress hormones, while spermatogonia alter RNA splicing.
    1. Cell Biology

    Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity

    Edward M Germany, Nakajohn Thewasano ... Takuya Shiota
    Bacterial outer membrane proteins are recognized by BamD at specific signals located in multiple β-strands at the C-terminus of these proteins, and this recognition is important for efficient outer membrane protein assembly and maintaining the integrity of outer membrane.
    1. Neuroscience

    Interaction of human keratinocytes and nerve fiber terminals at the neuro-cutaneous unit

    Christoph Erbacher, Sebastian Britz ... Nurcan Üçeyler
    Sensory nerve fiber ending ensheathment and connexin 43 contacts by keratinocytes at the neuro-cutaneous unit can be visualized and quantified at super-resolution in human skin.
    1. Computational and Systems Biology

    Homeostasis, injury, and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt

    Louis Gall, Carrie Duckworth ... Carmen Pin
    Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.