Browse our Research Articles

Multiple dynamic protein interactions converge to regulate the catalytic activity of the B cell kinase, BTK.

Characterization of the molecular mechanisms that enable azelaic acid, a secondary metabolite produced by photosynthetic organisms, to promote or inhibit different bacterial populations.

Combinations of inhibitors can more selectively inhibit individual or multiple protein kinases than single inhibitors.

Loss of functional dystroglycan disrupts the formation and function of CCK⁺/CB₁R⁺ inhibitory synapses in hippocampal CA1, resulting in reduced seizure thresholds in mouse models of dystroglycanopathy.

Comparative measurements and simulations of microtubule plus and minus end growth with mixed nucleotides demonstrate that nucleotide acts across a tubulin:tubulin interface to influence microtubule stability and dynamics.

Participants under acute stress were less willing to exert a relatively low level of physical effort for actions that benefit another person compared to actions that benefit themselves.

Counting the number of synaptic vesicles released in simple synapses under high release probability conditions revealed a maximum readily releasable pool size of two vesicles per docking site.

The structures of full-length Las1-Grc3 complexes provide crucial insights into the activation mechanism of HEPN nuclease and the pathway of pre-rRNA processing in ribosome biosynthesis.

The signaling requirements to decouple proliferation of pancreatic progenitors from differentiation were elucidated and employed for the reproducible expansion, under GMP-compliant conditions, of pancreatic progenitors derived from different human pluripotent stem cell lines.

The homeodomain protein Bsh increases lamina neuron types and visual function.