Browse our Research Articles

Spontaneous contractions allow shedding of the fluid boundary layer and thereby stabilize microbiota.

SUMOylated PCNA and the Elg1 PCNA unloader interact with the CST complex to coordinate DNA replication and telomere length maintenance.

Vitamin D bound to its receptor interacts with SIRT1 to induce its auto deacetylation and catalytic activity, which drives anti-proliferative effects in colorrectal cancer and this may lead to new therapeutic approaches for colorrectal and perhaps other cancers.

The transcriptional cofactor HPK-1 (homeodomain-interacting protein kinase) functions as a key regulator of multiple proteostatic stress responses, each originating from discrete neuronal subtypes within the Caenorhabditis elegans nervous system to preserve neuronal health and maintain organismal proteostasis during normal aging.

A biophysically detailed model of mouse primary visual cortex reproduces, in a quantitative manner, experimentally recorded spikes and local field potentials, and suggests mechanisms that form current sinks and sources in vivo.

In sensory ciliated neurons, FoxN4 Forkhead (FKH) transcription factors directly coregulate transcription of ciliome genes together with RFX transcription factors, a similar regulatory logic to what is found for motile-cilium cell types, suggesting an ancestral origin for this partnership.

Challenging a popular theory in neuroeconomics, a computational cognitive study provides evidence against divisive normalization, a supposedly canonical neural computation, in favor of an alternative account, range normalization, in the context of value learning.

Experimental work and computational models reveal how the timing between the inhibitory and excitatory inputs modulates the function of the inferior olive nucleus, a key structure for motor learning and cognition.

A 2-year field experiment reveals that plant secondary metabolites can be harnessed to increase crop productivity through plant-soil feedbacks under agronomically realistic conditions.

Extracellular glucose promotes O-GlcNAcylation of DNMT1 and inhibition of DNMT1 function in the maintenance of genomic methylation.