Javier Díaz-Alonso, Wade Morishita ... Roger A Nicoll
Despite being the key element of the classic model for excitatory synaptic plasticity, the cytoplasmic AMPA receptor C-tail is not required for hippocampal LTP.
The dynamics of neural responses during visual perception are best explained by a joint feedforward and recurrent architecture, which both maintains and broadcasts input features over time.
Cell cycle gating enables a temporal compartmentalization of negative vs positive feedback control processes, leading to differential responses to repetitive interferon stimulations.
Shreyasi Mukherjee, Praneet Chaturvedi ... Aaron M Zorn
Genomic analysis of Xenopus gastrula reveal that the transcription factor Sox17 interacts with the Wnt signaling effector ß-catenin on enhancers to regulate the transcriptional program underlying endoderm germ layer formation.
A single-trial whole-brain analysis of three cognitive strategies to attenuate pain shows that a more effective pain attenuation is associated with increased functional connectivity across the entire brain.
Matthew A Heinrich, Ricard Alert ... Daniel J Cohen
Epithelia exhibit size-dependent growth dynamics caused by a decoupling between boundary and bulk cellular dynamics that enable robust expansion and drive cell cycling, collective migration, and tissue-spanning vortices.
Kanji Okumoto, Mahmoud El Shermely ... Yukio Fujiki
H2O2-induced phosphorylation at Ser232 of Pex14 spatiotemporally regulates peroxisomal import of catalase, functioning in counteracting action against oxidative stress by the increase of cytosolic catalase.
Natalia Felipe-Medina, Sandrine Caburet ... Alberto M Pendás
Genetic and biochemical analysis reveal a variant in HSF2BP causing POI and C19ORF57/BRME1 as an interactor and stabilizer of HSF2BP by forming a complex with BRCA2, RAD51, RPA and PALB2.
