Metabolomic analyses indicate that diet generalism may stem from a neutral metabolic response to different chemistries, rather than from an accumulation of specific adaptations.
In juvenile songbirds, neural sequences pre-exist tutor exposure, and the process of learning a new song may make use of existing neural sequences as a stable substrate for new behavioral changes.
Oscillations that co-occur in hippocampal CA1 during exploration in the rodent are shown to segregate according to exploratory and sleep states in the primate.
Sheldon JJ Kwok, Daniel T Montoro ... Vladimir Vinarsky
Live imaging of cells in an intact murine tissue combined with single-cell sequencing reveals a unique transcriptional signature of an observed cellular behavior.
The cryo-EM structure of ETB-Gi complex, obtained using the Fusion-G system, provides insights into the distinct activation mechanism and G-protein promiscuity of ETB, aiding in the design of ETB agonists for therapeutic applications.
The important oncogene KRasG13C can be targeted by covalently binding nucleotide-analogues, resulting in a locked protein that can no longer induce oncogenic signaling.
Integrating multi-omics quantitative trait loci and genome-wide association study data into a multivariable Mendelian randomization framework allows to identify metabolite-mediated transcript-to-phenotype causal relations missed by methods focusing on a single omics layer.
Long COVID occurred in the majority of cancer patients diagnosed with acute COVID-19 with a preponderance of symptoms (such as fatigue, sleep disturbances, and gastrointestinal symptoms) over a long time period.
