Browse our Short Reports

Page 20 of 62
    1. Cancer Biology

    Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus

    Asieh Naderi, Elham Soltanmaohammadi ... Hippokratis Kiaris
    Monogamous rodents of the genus Peromyscus, upon disruption of pair bonds, acquire increased oncogenic activity.
    1. Immunology and Inflammation
    2. Medicine

    Bacterial–fungal interactions in the neonatal gut influence asthma outcomes later in life

    Rozlyn CT Boutin, Charisse Petersen ... B Brett Finlay
    Overgrowth of the yeast Pichia kudriavzevii within the neonatal gut microbiota increases allergic airway disease severity later in life and may be inhibited by short-chain fatty acids.
    1. Neuroscience

    Spontaneous and evoked activity patterns diverge over development

    Lilach Avitan, Zac Pujic ... Geoffrey J Goodhill
    Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.
    1. Developmental Biology

    Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

    Naokazu Inoue, Yoshihisa Hagihara, Ikuo Wada
    Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.
    1. Neuroscience

    Selective dendritic localization of mRNA in Drosophila mushroom body output neurons

    Jessica Mitchell, Carlas S Smith ... Scott Waddell
    Specific mRNAs localize to the dendrites of Drosophila mushroom body output neurons.
    1. Genetics and Genomics
    2. Medicine

    Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study

    Chiara Fallerini, Sergio Daga ... Elisa Frullanti
    In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.
    1. Neuroscience

    Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task

    Hongdian Yang, Bilal A Bari ... Daniel H O'Connor
    Correlations among LC spiking, membrane potential in S1 cortex, and pupil diameter vary within individual trials of a tactile detection task.
    1. Immunology and Inflammation

    Opposing effects of T cell receptor signal strength on CD4 T cells responding to acute versus chronic viral infection

    Marco Künzli, Peter Reuther ... Carolyn G King
    T cell receptor signal strength correlates positively with Th1 generation during acute infection but negatively during chronic infection.
    1. Cancer Biology

    Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation

    Yogev Sela, Jinyang Li ... Ben Z Stanger
    A photoconversion-based isolation technique enables systematic investigation of spatially distinct small metastases (microcolonies) versus large lesions (macrometastases).
    1. Neuroscience

    α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels

    Reeba Susan Jacob, Cédric Eichmann ... Philipp Selenko
    Plasma membrane clusters of the Parkinson's disease protein α-synuclein colocalize with negatively charged phospholipids involved in endocytosis and exocytosis.