Upon activation of T cell receptors at the contact site, T cells were substantially stiffened at the cell body as well as at the lamellipodia, which is mediated by Ca2+.
Psychometric measures reveal that, contrary to common assumption, rats have good visual form discrimination capacity under red and even far-red illumination.
Matthew C Bond, Lucia Vidakovic ... Carey D Nadell
Microfluidic culture and high-resolution 3-D microscopy establish that bacteriophages trapped in the outer matrix layers of a bacterial biofilm remain active and can prevent colonization of the biofilm by newly arriving bacteria.
Surender Rajasekaran, Caleb P Bupp ... André S Bachmann
Genetic sequencing has led to the increased diagnoses of rare diseases, strategies such as repurposing drugs and global metabolomics offer promise and bring hope to afflicted families.
Maria Eugenia Dieterle, Carles Solà-Riera ... Kartik Chandran
Several previously proposed cell-surface receptors for hantaviruses could be deleted in endothelial cells with little or no effect on infection, indicating that critical hantavirus entry factors remain undiscovered.
Cerebellar degeneration disrupts the use of interval-based temporal cues, but not rhythmic cues, to proactively modulate perceptual sensitivity, implicating the cerebellum in temporal control of visual attention.
The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.
Alessandra Gentile, Anabela Bensimon-Brito ... Didier YR Stainier
The transcription factor Snai1b maintains the myocardial wall integrity by limiting cell extrusions and regulating the intermediate filament gene desmin b.
