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A murine model for a novel surgical concept demonstrates potential advances of neuroprosthetic interfacing.

Delivery of auditory triggers as unique slow waves-targeting approach yields efficient, stable, and precise modulation of slow-wave activity in rats.

A robust automatic sleep-staging algorithm offers a high level of accuracy matching that of typical human interscorer agreement.

Descriptions, examples, and tools to enable biologists to use the Common Workflow Language for data processing and to facilitate computational reproducibility.

Time-resolved transition metal ion fluorescence resonance energy transfer using a fluorescent, noncanonical amino acid donor and metal ion acceptor measures distances and distance distributions in proteins, allowing the equilibrium distributions among conformational states to be accurately determined.

Bayesian estimation of the proportion of the population that would show an effect in an experiment provides a broadly applicable alternative to standard null hypothesis tests on the population mean with several advantages.

A serum-free organotypic culture model of mouse lung epithelial progenitors was developed and used to screen WNT modulators for regulators of epithelial differentiation.

The microenvironment surrounding sensory neurons in dorsal root ganglia responds differently to peripheral and central injuries, revealing that non-neuronal cells can be manipulated to promote axon regeneration after central injury.

A broadly applicable deep-learning based method that recognizes rod-shaped bacteria of virtually any species in complex bacterial communities.

A comprehensive package for pedigree-based risk modeling, with a highly optimized computational back-end, extends existing models beyond syndrome-specific approaches and incorporates data from panel studies by allowing for an arbitrary number of gene and syndrome associations.