Browse our Tools and Resources

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    1. Neuroscience

    A 3D adult zebrafish brain atlas (AZBA) for the digital age

    Justin W Kenney, Patrick E Steadman ... Paul W Frankland
    A new tool for three-dimensional exploration of adult zebrafish neuroanatomy.
    1. Neuroscience

    The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice

    Cristina Segalin, Jalani Williams ... Ann Kennedy
    The Mouse Action Recognition System is a computational pipeline for automated classification of social behaviors in freely interacting mice, accompanied by a graphical interface for analysis of multimodal neuroscience datasets.
    1. Neuroscience

    A parameter-free statistical test for neuronal responsiveness

    Jorrit S Montijn, Koen Seignette ... J Alexander Heimel
    A simple and robust statistical test for neuronal stimulus response, that outperforms PSTH-based approaches such as t-tests and ANOVAs.
    1. Neuroscience

    Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei

    Zhengchao Xu, Zhao Feng ... Anan Li
    Whole-brain quantitative input-output circuits of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei were mapped using viral tracing and high-resolution optical imaging.
    1. Neuroscience

    Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons

    Minh Q Nguyen, Lars J von Buchholtz ... Steve Davidson
    Single-nucleus transcriptomics exposes unique features of human somatosensory neurons and clues that may help resolve repeated problems in translating new experimental approaches for treating pain.
    1. Neuroscience

    Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

    Austin R Graves, Richard H Roth ... Richard L Huganir
    A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.
    1. Cell Biology
    2. Ecology

    Monitoring single-cell dynamics of entry into quiescence during an unperturbed life cycle

    Basile Jacquel, Théo Aspert ... Gilles Charvin
    A switch-like cell fate divergence revealed by continuous single-cell tracking during entry into quiescence.
    1. Developmental Biology
    2. Neuroscience

    A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation

    Jie Wang, Amir Rattner, Jeremy Nathans
    Using single nucleus RNA sequencing, a complete catalogue of cell types was determined for the mouse iris, and this information was used as a starting point to define the effects of pupil dilation on gene expression and on nuclear morphology.
    1. Genetics and Genomics
    2. Neuroscience

    Parallel functional testing identifies enhancers active in early postnatal mouse brain

    Jason T Lambert, Linda Su-Feher ... Alex S Nord
    Methods for screening hundreds of DNA sequences for enhancer activity have been extended for use in vivo, uncovering novel enhancer elements active in the early postnatal brain.
    1. Neuroscience

    Fast and accurate annotation of acoustic signals with deep neural networks

    Elsa Steinfath, Adrian Palacios-Muñoz ... Jan Clemens
    DAS is a universal tool for segmenting and identifying acoustic signals in single and multi channel recordings robustly, reliably, and at low latency.