High-quality, multimodal, electrophysiological, morphological, and transcriptomic data collection from a single cell using a refined Patch-seq protocol.
Derek S Lundberg, Pratchaya Pramoj Na Ayutthaya ... Detlef Weigel
hamPCR is a cost-effective and transformative amplicon sequencing strategy to describe microbiota composition and measure its overall abundance, applicable to all samples in which host and microbial DNA are co-extracted.
Image3C is a new image-based analysis of cell population composition for research organisms in which detailed cellular phenotypes are unknown or for which species-specific reagents are not available.
DNA nanodevices can be targeted to specific cell types in Caenorhabditis elegans with subcellular precision by exploiting either endogenous or synthetic receptors.
Live-cell imaging captures the heterogenity of bacterial growth within intracellular bacterial communities and demonstrates that the constituent bacteria are protected from clearance by antibiotics delivered with a physiologically relevant pharmacodynamic profile.