Browse the latest research

Page 292 of 1,782
    1. Evolutionary Biology

    Evolution and diversity of biomineralized columnar architecture in early Cambrian phosphatic-shelled brachiopods

    Zhiliang Zhang, Zhifei Zhang ... Guoxiang Li
    Columnar architectures, developed in early Cambrian phosphatic-shelled brachiopods, are highly biologically controlled and organic-matrix mediated, which sheds new light on the evolution and adaptation of biomineralization during the Cambrian explosion.
    1. Biochemistry and Chemical Biology

    The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

    Valentin Bohl, Nele Merret Hollmann ... Axel Mogk
    The bacterial AAA+ chaperone ClpL recognizes aggregated proteins via multiple contacts of its unique N-terminal domain and refolds them with high efficiency providing superior heat resistance.
    1. Physics of Living Systems

    Substrate evaporation drives collective construction in termites

    Giulio Facchini, Alann Rathery ... Andrea Perna
    Evidence of a relationship between substrate curvature, water evaporation and the building behavior of termites capable of mediating collective nest-building with no need for a building pheromone.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Effect of α-tubulin acetylation on the doublet microtubule structure

    Shun Kai Yang, Shintaroh Kubo ... Khanh Huy Bui
    Cryo-EM studies of doublet microtubules from wild-type and acetylation mutants suggest that acetylation of K40 affects the lateral rotational angle between protofilaments, leading to changes in the structure and stability.
    1. Developmental Biology
    2. Neuroscience

    Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells

    Smrithi Prem, Bharati Dev ... Emanuel DiCicco-Bloom
    Alterations in mTOR signaling drive similar dysregulations in the critical mid-fetal neurodevelopmental processes of neurite outgrowth and cell migration in two distinct subsets of autism, idiopathic and 16p11.2 deletion.
    1. Neuroscience

    Mining the neuroimaging literature

    Jérôme Dockès, Kendra Oudyk ... Jean-Baptiste Poline
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli

    Sebastian Jojoa-Cruz, Adrienne E Dubin ... Andrew B Ward
    Structural comparison and electrophysiology of OSCA channels shed light on potential structural features influencing response to poke stimulus.
    1. Neuroscience

    Neural correlates of perceptual similarity masking in primate V1

    Spencer Chin-Yu Chen, Yuzhi Chen ... Eyal Seidemann
    Optical imaging from macaque monkeys performing a detection task reveals the contribution of neural populations in V1 to the phenomenon of camouflage, where detectability decreases with target-background similarity.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization

    Tien M Phan, Young C Kim ... Jeetain Mittal
    Despite highly conserved sequences, subtle variations in HP1 paralog charge distribution influence distinct liquid-liquid phase separation behaviors, ultimately impacting DNA-mediated heterochromatin organization.