Browse the latest research

Page 3 of 1,875
    1. Neuroscience
    2. Physics of Living Systems

    A deep learning pipeline for mapping in situ network-level neurovascular coupling in multi-photon fluorescence microscopy

    Matthew W Rozak, James R Mester ... Bojana Stefanovic
    A novel pipeline for analyzing longitudinal two-photon microscopy data of cerebrovasculature in mice interrogates the vasculature network before and after optogenetic stimulation, revealing new insights into their coordination.
    1. Neuroscience

    Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions

    Maria Gädeke, Tom Eric Willems ... Johannes Schultz
    Being responsible for a partner's adverse outcomes is associated with anterior insula activation, while the superior temporal sulcus tracks prediction errors for the partner's reward resulting from the participant's decisions.
    1. Computational and Systems Biology
    2. Neuroscience

    Visual information is broadcast among cortical areas in discrete channels

    Yiyi Yu, Jeffery N Stirman ... Spencer LaVere Smith
    Activity fluctuations, or noise correlations, are robust measures of neuronal connectivity and they reveal that neural circuity controls mixing of information at a granular level across millimeter-length scales.
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Adaptor protein supersaturation drives innate immune signaling and cell fate

    Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann
    In-cell biophysical analyses identify a sequence-encoded energy storage function of innate immune adaptor proteins that allows cells to respond quickly and decisively to pathogenic signals.
    1. Cancer Biology
    2. Immunology and Inflammation

    The 1000+ mouse project for large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Y Altan-Bonnet
    An automated bioluminescent image analysis framework, maRQup, parametrizes tumor dynamics and provides quantitative metrics, enabling large-scale evaluation and optimization of preclinical cancer immunotherapies.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Human genetic ancestry, Mycobacterium tuberculosis diversity, and tuberculosis disease severity in Dar es Salaam, Tanzania

    Michaela Zwyer, Zhi Ming Xu ... Daniela Brites
    The severity of active tuberculosis in a high-burden population is not explained by host or pathogen genetic variation, suggesting a dominant role for social and environmental factors.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

    Yuzhen Liu, Christopher D McGann ... Devin K Schweppe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

    Lori B Koch, Tiasha Ghosh ... Adele L Marston
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Overt visual attention modulates decision-related signals in ventral and dorsal medial prefrontal cortex

    Blair RK Shevlin, Rachael Gwinn ... Ian Krajbich
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing