Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
In vitro reconstitution identifies how lysosome-related vacuoles coordinate the synthesis and turnover of inorganic polyphosphates to create a powerful buffer system stabilising a vital metabolic parameter, the cytosolic concentration of phosphate.
Sarah G Donofrio, Cheryl Brandenburg ... Roy V Sillitoe
Purkinje cell subpopulations have varying vulnerability to age-related neurodegeneration, creating a striped pattern of cell loss that reflects the developmental, anatomical, and functional organization of the cerebellum.
A normative computational model of individual differences in mouse exploration driven by reward and threat uncertainty as well as risk sensitivity when faced with a novel object in an open field.
Pablo Ruiz Cuenca, Fábio N Souza ... Emanuele Giorgi
Step selection functions are a useful tool for analysing fine-scale human movements to understand environmental interactions in the context of infectious disease epidemiology.
Ramesh Chittajallu, Anna Vlachos ... Chris J McBain
A pharmacogenetic approach provides a foundational dataset describing the influence of opioids on synaptic processing in a brain microcircuit known to be critical for driving hedonic behaviors.