Browse the latest research

Page 7 of 1,889
    1. Cancer Biology

    Molecular architecture of the tumor microenvironment caused by BRCA1 and BRCA2 somatic mutations in lung adenocarcinoma

    Gaoming Liao, Xinbin Yang ... Gang Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Use-dependent regulation of the axonal action potential in parvalbumin-expressing interneurons

    Sophie R Liebergall, Ethan M Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    A single-cell transcriptomic atlas of inner ear morphogenesis in zebrafish

    Akankshi Munjal, Kalki Kukreja ... Ian A Swinburne
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Genetics and Genomics
    2. Cancer Biology

    Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8

    Hyunkyung Kong, Jiyeon Choi ... Kevin M Brown
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the recruitment of viral Type 2 IRES to ribosomal preinitiation complex for protein synthesis

    Deepakash Das, Tanweer Hussain
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    Host and antibiotic jointly select for greater virulence in Staphylococcus aureus

    Michelle Su, Kim L Hoang ... Timothy D Read
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Endometrial epithelial cells with high ALDH activity control uterine development and regeneration

    Suni Tang, Anna Catherine Unser ... Diana Monsivais
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Metabolic basis of the astrocyte-synapse interaction governs dopaminergic-motor connection

    Yanru Xu, Piaoping Kong ... Zhiguo Ma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels

    Soenke Cordeiro, Robert Patejdl ... Marianne A Musinszki
    Identification of mangostins as potent BK channel activators links natural xanthones to vascular smooth muscle relaxation, providing a mechanistic basis for their reported antihypertensive effects.
    1. Computational and Systems Biology

    Dynamic architecture of mycobacterial outer membranes revealed by all-atom simulations

    Turner P Brown, Matthieu Chavent, Wonpil Im
    The first all-atom models of the mycobacterial outer membrane reveal how lipid organization and asymmetry generate a structurally heterogeneous barrier that underlies its unique permeability properties.
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